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Deep learning, self-supervised algorithm for fast and accurate image registration
Deep learning, self-supervised algorithm for fast and accurate image registration Brief DescriptionA deep learning algorithm for fast and accurate, non-rigid image registration that does not require a training data set. ProblemMedical image registration is necessary for aligning multiple clinical images from a single patient as well as for associa...
Published: 4/5/2019   |   Inventor(s): Yong Fan
Keywords(s):  
Category(s): Imaging, Software, Data, Algorithms, & Apps
Discovery of diazaxanthylidenes for live cell molecular imaging, cell activation, and binding disease-relevant nucleic acids
Brief Description: Synthesis of organelle-specific photoactivatable fluorescent probes for live cell imagingTechnology:The Chenoweth lab has uncovered a synthetic route to generate fluorescent compound libraries from a diazaxanthilidene scaffold of the azaxanthone family that can be used for organelle-specific staining, live cell molecular imaging,...
Published: 3/1/2019   |   Inventor(s): David Chenoweth
Keywords(s):  
Category(s): Chemical Processes and Synthesis, Imaging, Research Tools & Reagents
Antibodies for Targeting CAR-T Cells to Neuroendocrine Tumors
Neuroendocrine tumors (NETs) pose serious threats to patients’ well-being as malignant diseases, and most patients with metastatic NETs succumb to the disease. Using Sequential Tumor-related Antibody and antigen Retrieving (STAR) technology Dr. Xianxin Hua, MD, PhD at the University of Pennsylvania Medical School and his team have identified ...
Published: 3/1/2019   |   Inventor(s): Xianxin Hua
Keywords(s):  
Category(s): Diagnostics, Imaging, Therapeutics & Vaccines
Improved PARP Inhibitors for Imaging and Treatment of Cancer and Neurodegenerative Diseases
Novel high-affinity PARP inhibitors with various properties for imagining and treating cancer and inflammation-related diseasesTechnology:The poly(ADP-ribose) polymersase-1 (PARP-1) enzyme is heavily involved in propagating neurodegeneration and cancer. In neurodegeneration PARP-1 causes cell death, while in cancer PARP-1 acts as DNA damage respons...
Published: 1/28/2019   |   Inventor(s): Robert Mach
Keywords(s):  
Category(s): Imaging, Research Tools & Reagents, Therapeutics & Vaccines
Polarization-based shadow analysis
Capturing hidden details with polarized lightInventorNader Engheta ProblemMost cameras only capture information on the intensity and color of light. Polarization is another characteristic of light that can provide useful information, but conventional cameras do not provide polarization data. Shadows pose a difficult problem for machine vision and ...
Published: 11/27/2018   |   Inventor(s): Nader Engheta
Keywords(s):  
Category(s): Imaging
Polarization imaging
Polarization imaging sensor for enhanced scene analysisInventorNader Engheta & Jan Van der Spiegel ProblemAlong with intensity and color, polarization is a property of light that can provide useful information for scene analysis. However, the human eye and most cameras cannot detect polarization. Gathering polarization data could aid machine vi...
Published: 11/27/2018   |   Inventor(s): Nader Engheta, Jan Van Der Spiegel
Keywords(s):  
Category(s): Hardware, Circuits, & Sensors, Imaging
129Xe biosensors for molecular imaging in lungs and brain and potential early detection of breast cancer
Cell-compatible cryptophanes and functionalized 129Xe contrast agents for in vivo highly sensitive NMR and MRI measurements of cancer cellsInventorIvan Dmochowski, Professor of ChemistryProblemCurrent breast cancer screening strategies rely on identifying morphological changes in tissue. There is not a single biomarker to identify early breast can...
Published: 11/27/2018   |   Inventor(s): Ivan Dmochowski
Keywords(s): Biological SensorsĀ , Reagents
Category(s): Diagnostics, Research Tools & Reagents, Imaging
Non-contact Fingerprint Scanner
Latent fingerprint detection using non-destructive imagingInventorNader Engheta ProblemLatent fingerprints, the marks left by contact with a surface, have been used by forensic science since the 19th century. Often the fingerprints left on objects of interest are hard to detect with the unaided eye, and they may be only partial prints or of low ...
Published: 11/27/2018   |   Inventor(s): Nader Engheta
Keywords(s):  
Category(s): Imaging
CT-like Bone Imaging using MRI
Method to produce CT-like 3D images of bones and hard tissue from MRI sequences.Inventors: Felix W. Wehrli, Scott P. Bartlett, Hyunyeol Lee, Rosaline ZhangProblemComputed tomography (CT) is an imaging technique that enables 3D visualization of skeletal tissue. However, CT imaging exposes patients to hazardous radiation, which can be problematic for...
Published: 9/24/2018   |   Inventor(s): Felix Wehrli, Scott Bartlett, Hyunyeol Lee, Rosaline Zhang
Keywords(s):  
Category(s): Imaging, Software, Data, Algorithms, & Apps
Method for Rapid 3D Printing from Medical Images
Method and software product allowing for direct conversion of any three dimensional image (e.g., CT, MRI, ultrasound, PET, etc.) into 3D printable instructions (i.e., G-Code).InventorChamith Rajapakse, Ph.D.ProblemMedical Digital Imaging and Communications in Medicine (DICOM) image files generated by CT or MRI scanners can be utilized to generate t...
Published: 7/27/2018   |   Inventor(s): Chamith Rajapakse
Keywords(s):  
Category(s): Imaging, Software, Data, Algorithms, & Apps, IT, Communication, & Networking, Medical Devices, Research Tools & Reagents
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