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Search Results - andrew tsourkas

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A versatile universal immune receptor platform for generating targeted cellular immunotherapies
Platform for spontaneous, covalent linkage of any antigen-binding moiety to an engineered immune receptor on the surface of an immune cellInventorDaniel J. Powell Jr., Ph.D., Research Associate Professor of Pathology and Laboratory Medicine Andrew Tsourkas, Ph.D, Professor of Bioengineering and Associate Director, Center for Targeted Therapeutics a...
Published: 6/1/2016   |   Inventor(s): Daniel Powell, Andrew Tsourkas
Keywords(s):  
Category(s): Therapeutics & Vaccines, Diagnostics, Imaging
Optical probes for real-time nucleic acid detection and gene expression analysis in living cells
Fluorescent ratiometric bimolecular beacons with spatiotemporal resolutionInventorAndrew Tsourkas, Professor of BioengineeringProblemCommon gene expression analysis methods, including polymerase chain reaction, microarrays, and in situ hybridization rely on fixed or lysed cells, hindering their ability to provide spatiotemporal information. This h...
Published: 1/20/2016   |   Inventor(s): Andrew Tsourkas
Keywords(s): Biological Sensors , Biotechnology, Optics & Photonics 
Category(s): Diagnostics, Research Tools & Reagents, Therapeutics & Vaccines, Imaging
Single step protein purification and site-specific bioconjugation
Sortase-mediated expressed protein ligation and bioconjugation for molecular imaging and targeted therapeuticsInventorAndrew Tsourkas, Professor, Department of BioengineeringTechnology OverviewThe Tsourkas lab has developed a novel conjugation technique that allows any single-chain recombinant protein to be site-specifically modified at the C-termi...
Published: 8/31/2015   |   Inventor(s): Andrew Tsourkas
Keywords(s): Biotechnology, Engineering
Category(s): Research Tools & Reagents, Imaging, Chemical Processes and Synthesis
Site-specific bioconjugation of native immunoglobulins
Method for covalent cross-linking of antibodies to surfaces for immunoassays and targeted drug deliveryInventorAndrew Tsourkas, Professor, Department of Bioengineering Technology OverviewThe Tsourkas lab has designed a facile method for the site-specific bioconjugation of native immunoglobulins (IgGs). The researchers have developed novel photorea...
Published: 8/31/2015   |   Inventor(s): Andrew Tsourkas
Keywords(s): Biotechnology, Engineering
Category(s): Research Tools & Reagents, Therapeutics & Vaccines, Imaging, Chemical Processes and Synthesis