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A method to identify modulators for regulatory T cell functions
Docket # T4518 Technology OverviewMaintenance of tolerance to self-antigens is essential for the prevention of autoimmunity. This process is known to involve specific regulatory T cells (Treg) and the expression of the forkhead family transcription factor, FOXP3. FOXP3 is a “sufficient” regulator of the development and function of peri...
Published: 8/10/2017   |   Inventor(s): Mark Greene
Keywords(s): Autoimmune, Biotechnology
Category(s): Research Tools & Reagents
Monoclonal antibody to CXCR6
Brief DescriptionCXCR6 is a chemokine receptor expressed by leukocytes and other cells, and is believed to play a role in cancer metastasis, gut mucosal integrity, autoimmunity, diabetes and other inflammatory disorders. It is also used by SIV as a co-receptor for target cell entry.Docket # 15-7418 Technology OverviewCurrent commercially availab...
Published: 5/7/2015   |   Inventor(s): Ronald Collman
Keywords(s): Antibody, Autoimmune, Cancer, Reagents: Antibodies, Research Tool
Category(s): Research Tools & Reagents