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Search Results - brian litt

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Implantable Device to Treat Epilepsy
Diagnostic and preventative implantable device with computer-brain interface for treatment of epilepsy.InventorBrian Litt, MD, Department of Neurology ProblemOne percent of the world’s population suffers from epilepsy. Aside from seizures’ debilitating effects, patients are confined by their unpredictability. Prevention is one way to de...
Published: 11/27/2018   |   Inventor(s): Brian Litt
Keywords(s): Biological Sensors , Biomedical Engineering
Category(s): IT, Communication, & Networking, Diagnostics, Therapeutics & Vaccines, Materials, Medical Devices
2D Metal Carbides and Nitrides (MXenes) Electrodes
ProblemCurrent implantable devices for recording and stimulating electrical activity in the body are fabricated with metal based components. Which pose issues for long term implantation and functionality, including scarring, inflammation, degradation and fatigue. Furthermore, the physical properties of metals are typically inadequate to achieve goo...
Published: 7/17/2018   |   Inventor(s): Flavia Vitale, Brian Litt
Keywords(s):  
Category(s): Diagnostics, Medical Devices
High spatial and temporal resolution mapping of brain activity using flexible multiplexed electrode arrays with long term stability and safety
Flexible foldable actively multiplexed high density electrode array for mapping brain activity in-vivoInventorBrian Litt, MD, Department of NeurologyProblemElectrode arrays for recording and stimulating the brain are used throughout clinical medicine and basic neuroscience research, but are unable to sample large areas of the brain while maintainin...
Published: 2/4/2016   |   Inventor(s): Brian Litt
Keywords(s): Biological Sensors , Neurodegenerative Diseases
Category(s): Diagnostics, Medical Devices
Measuring and manipulating neuronal signals using implantable electronic microsensor arrays
Self-Adaptive, High Density, Flexible Neuronal Sensor-Effector Microarray for Diagnosis and Treatment of Brain, Spine, Peripheral, and Cardiac NeuropathiesInventorBrian Litt, MD, Department of NeurologyProblemMost current implantable brain devices stimulate large regions of the brain without sensing. These devices are not able to access the fine mu...
Published: 2/3/2016   |   Inventor(s): Brian Litt
Keywords(s): Biological Sensors , Neurodegenerative Diseases
Category(s): Diagnostics, Medical Devices
Classifying high-frequency oscillations in physiological recordings
Method for Automatic and Unsupervised Classification of High-Frequency Oscillations in Physiological Recordings InventorBrian Litt, MD, Department of Neurology ProblemAutomatic detection and classification of high frequency oscillations (HFO) data for use in clinical diagnosis and therapy has been limited. Currently, researchers visually inspect fo...
Published: 2/3/2016   |   Inventor(s): Brian Litt
Keywords(s): Biomedical Engineering, Engineering, Neurodegenerative Diseases
Category(s): Research Tools & Reagents, IT, Communication, & Networking, Imaging, Medical Devices
Electrodes for Long Term In-vivo Implantation and In-vitro use
Brief DescriptionGraphene-Passivated Implantable Electrodes Docket # Z6751 ProblemImplantable devices for use in the body of a subject, such as neural prosthetic systems, have had limited success due to the challenges presented by the environment the devices are exposed to. Long-term interaction with the implantable device and the body takes a to...
Published: 5/15/2015   |   Inventor(s): Brian Litt
Keywords(s): Graphene, Implants
Category(s): Medical Devices
Transparent graphene electrodes to image and monitor biological tissues
Brief DescriptionTransparent electrode arrays for visualization, simultaneous imaging, and electrophysiologyDocket # 14-7016 ProblemCalcium imaging is a versatile tool capable of resolving single neurons and their connectivity with single-cell spatial resolution in the brain. Unfortunately, its coarse temporal resolution limits its ability to dete...
Published: 5/8/2015   |   Inventor(s): Brian Litt
Keywords(s): Biological Sensors , Graphene
Category(s): Materials, Diagnostics