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Search Results - changchun liu

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High efficiency, superhydrophobic clamshell plasma separator for point-of-care diagnostics
Membrane-based, sedimentation-assisted plasma separator InventorHaim H. Bau, Professor of Mechanical Engineering and Applied MechanicsChangchun Liu, Assistant Research ProfessorMichael Mauk, Visiting Assistant Clinical ProfessorProblemHigh sensitivity, point-of-care clinical tests, such as HIV viral load, require large volumes of plasma extracted from...
Published: 1/31/2018   |   Inventor(s): Haim Bau, Changchun Liu, Michael Mauk
Keywords(s): Engineering
Category(s): Diagnostics, Medical Devices
A pouch-based cassette for bio-detection with timer-based actuator
Brief Description: Bio-detection cassette with automated actuator for self-contained immunoassay devices and lab-on-a-chip assaysTechnology:The Bau lab has developed a device that sequentially delivers multiple reagents into a microfluidics based lab-on-a-chip system. Protrusions on a rotating wheel sequentially press plastic balls onto flexible diaphragms,...
Published: 2/8/2017   |   Inventor(s): Haim Bau, Changchun Liu
Keywords(s):  
Category(s): Diagnostics, Medical Devices
A membrane-based, high-efficiency microfluidic debubbler for point-of-care devices
Brief Description: Debubbler for microfluidic systems -----------------------------------------------------------------------------------------------------------------------------------------Technology:Problem: Microfluidic devices often suffer from unwanted bubbles inside a channel, resulting in obstructed fluidic paths, lower reaction efficiency,...
Published: 1/10/2017   |   Inventor(s): Haim Bau, Changchun Liu
Keywords(s):  
Category(s): Diagnostics, Medical Devices, Research Tools & Reagents
A disposable self-heating cartridge for point-of-care molecular diagnostics
Brief Description: A water-activated, self-heating, instrument-free microfluidic diagnostic cartridge-----------------------------------------------------------------------------------------------------------------------------------------Technology:Problem: Many molecular diagnostic devices require elevated temperatures to carry out biochemical reactions,...
Published: 1/3/2017   |   Inventor(s): Changchun Liu, Haim Bau
Keywords(s):  
Category(s): Diagnostics, Medical Devices, Research Tools & Reagents
Method and microfluidic chip for two-stage multiplexed isothermal enzymatic amplification
On-chip two-step nucleic acid amplification for point-of-care and clinical molecular detection of multiple diseases and co-infectionsInventorsHaim H. Bau, Professor of Mechanical Engineering & Applied MechanicsChangchun Liu, Assistant Research Professor, Mechanical Engineering & Applied MechanicsProblemPolymerase chain reaction methods (PCR)...
Published: 7/8/2016   |   Inventor(s): Haim Bau, Changchun Liu
Keywords(s):  
Category(s): Diagnostics, Medical Devices, Research Tools & Reagents
A reverse transcription loop-mediated isothermal amplification method to quantify multiple HIV subtypes
A rapid, quantitative point-of-care diagnostics method for viral load detection of HIV-1 clades A, B, C, D, and GInventorHaim H. Bau, Professor of Mechanical Engineering and Applied MechanicsChangchun Liu, Research Assistant Professor, Mechanical Engineering and Applied MechanicsFrederic D. Bushman, Professor of MicrobiologyProblemHIV infection remains...
Published: 1/20/2016   |   Inventor(s): Haim Bau, Changchun Liu, Frederic Bushman
Keywords(s): Biotechnology, Engineering
Category(s): Diagnostics, Research Tools & Reagents, Medical Devices
Nuclemeter: a yardstick for quantifying nucleic acids undergoing enzymatic amplification
Point-of-care, reaction-diffusion column-based, non-instrumented device for real-time visual measurement of viral load in resource-limited settings, in the clinic, and at homeInventorHaim H. Bau, Professor of Mechanical Engineering and Applied MechanicsChangchun Liu, Research Assistant Professor, Mechanical Engineering and Applied MechanicsMichael G....
Published: 1/20/2016   |   Inventor(s): Haim Bau, Changchun Liu, Michael Mauk
Keywords(s): Engineering, Nanotechnology
Category(s): Diagnostics, Research Tools & Reagents
Rapid plasma separator for point-of-care diagnostics and viral load detection that does not require electrical power
Membrane-based, sedimentation-assisted plasma separator from whole blood for clinical testsInventorHaim H. Bau, Professor of Mechanical Engineering and Applied MechanicsChangchun Liu, Assistant Research ProfessorMichael Mauk, Visiting Assistant Clinical ProfessorProblemHigh sensitivity, point-of-care clinical tests, such as HIV load, require large volumes...
Published: 12/8/2015   |   Inventor(s): Haim Bau, Changchun Liu, Michael Mauk
Keywords(s):  
Category(s): Diagnostics, Medical Devices