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Search Results - daniel powell

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Single viral vector for expression of both CAR/TCR and immune modulators for cancer immunotherapy
A single lentiviral vector system as an expression platform for constitutive immune receptor expression and inducible antigen-dependent immunomodulatory molecule expression in primary immune cells for enhanced immunotherapy efficacyProblemAdoptive cancer immunotherapy, like chimeric antigen receptor T cell (CAR T) therapy, has had extraordinary cli...
Published: 1/23/2019   |   Inventor(s): Daniel Powell, Anze Smole, Avery Posey
Keywords(s):  
Category(s): Research Tools & Reagents, Therapeutics & Vaccines
A versatile universal immune receptor platform for generating targeted cellular immunotherapies
Platform for spontaneous, covalent linkage of any antigen-binding moiety to an engineered immune receptor on the surface of an immune cellInventorDaniel J. Powell Jr., Ph.D., Research Associate Professor of Pathology and Laboratory Medicine Andrew Tsourkas, Ph.D, Professor of Bioengineering and Associate Director, Center for Targeted Therapeutics a...
Published: 6/1/2016   |   Inventor(s): Daniel Powell, Andrew Tsourkas
Keywords(s):  
Category(s): Therapeutics & Vaccines, Diagnostics, Imaging