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A method for highly selective nucleic acid enrichment for sensitive detection of mutations in cancer and genectic conditions.
This technology increases the fraction of clinically relevant, rare mutant alleles (DNA and/or RNA) to enable high sensitivity detection with common downstream methods such as capped (XNA or PNA) PCR, ddPCR, and sequencing. Problem:Liquid biopsy is a simple, minimally invasive, rapidly developing diagnostic method to analyze cell-free nucleic acid ...
Published: 6/24/2019   |   Inventor(s): Jinzhao Song, Haim Bau, Michael Mauk, Jorrit Hegge, John van der Oost
Keywords(s):  
Category(s): Diagnostics, Hardware, Circuits, & Sensors, Medical Devices, Research Tools & Reagents, Veterinary & Animal Health