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Targeting the retinoic acid pathway to bolster immunotherapy
A strategy to potentiate immune checkpoint blockade by targeting retinoic acid signaling in immunosuppressive solid tumors.Technology:Sarcomas are solid tumors with more than 70 rare and often fatal subtypes. Typical survival rates are under 15 % over 5 years. Sarcomas can prevent the formation of tumor-killing cells by eluding immune detection, a ...
Published: 6/5/2019   |   Inventor(s): Malay Haldar, Samirkumar Devalaraja
Keywords(s):  
Category(s): Therapeutics & Vaccines