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Novel “DNA trapping” and “Non-trapping” PARP Inhibitors
Candidate PARPi compounds with strong anti-cancer capabilities (i.e. “DNA trappers”) and PARPi candidates with low cellular toxicity for treatment of stroke, diabetes, myocardial infarction, neurodegenerative diseases and other diseases with PARP overactivation (i.e. “non-trappers”).Technology:Inhibition of Poly(ADP‐ribose) ...
Published: 6/3/2019   |   Inventor(s): Ben Black, Tanaji Talele, John Pascal
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Category(s): Research Tools & Reagents, Therapeutics & Vaccines