Available Technologies

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Search Results - veterinary & animal health

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A method for highly selective nucleic acid enrichment for sensitive detection of mutations in cancer and genectic conditions.
This technology increases the fraction of clinically relevant, rare mutant alleles (DNA and/or RNA) to enable high sensitivity detection with common downstream methods such as capped (XNA or PNA) PCR, ddPCR, and sequencing. Problem:Liquid biopsy is a simple, minimally invasive, rapidly developing diagnostic method to analyze cell-free nucleic acid ...
Published: 6/24/2019   |   Inventor(s): Jinzhao Song, Haim Bau, Michael Mauk, Jorrit Hegge, John van der Oost
Keywords(s):  
Category(s): Diagnostics, Hardware, Circuits, & Sensors, Medical Devices, Research Tools & Reagents, Veterinary & Animal Health
Protein Sequences for Therapeutic Applications in Management of Obesity, Cachexia and Nausea
Non-naturally occurring protein sequences that enhance or suppress the activity of hormone associated with obesity and nauseaProblem (or motivation)Growth differentiation factor-15 (GDF15) is a broadly expressed hormone, whose level often correlates with progression of many diseases. It has been shown in multiple species that the elevated level of ...
Published: 3/27/2019   |   Inventor(s): Ian Tinsley, Tito Borner, Robert Doyle, Bart De Jonghe, Matthew Hayes
Keywords(s):  
Category(s): Therapeutics & Vaccines, Veterinary & Animal Health
Gene therapy for the treatment of retinal degeneration and vision loss
Brief Description:Recombinant adeno-associated virus (rAAV) expressing the gene for retinitis pigmentosa GTPAse regulation (RPGR) for the functional and structural rescue of photoreceptor cells of the eye as gene therapy for retinal degeneration and vision loss.Technology:Retinitis pigmentosa (RP) is a genetic form of early-onset retinal degenerati...
Published: 6/7/2018   |   Inventor(s): William Beltran, Gustavo Aguirre, Artur Cideciyan, Samuel Jacobson
Keywords(s):  
Category(s): Therapeutics & Vaccines, Veterinary & Animal Health
New therapy for skin infections in companion animals
Brief Description: A selective method for treating bacterial skin and ear infections in dogs, cats and horses. -----------------------------------------------------------------------------------------------------------------------------------------Technology: Problem: Pyoderma, or bacterial infection of the skin, is the most common dermatologic p...
Published: 12/22/2016   |   Inventor(s): Daniel Beiting
Keywords(s):  
Category(s): Veterinary & Animal Health
Device to produce traumatic brain injury in model organisms
Brief Description: Research tool for immobilizing animal and precisely inflicting head traumaTechnology:Problem: Traumatic brain injury (TBI) is a leading cause of neurological deficits, resulting from mechanical forces that deform the brain, along with secondary injuries triggered by molecular responses. TBI outcomes are heterogeneous due to the ...
Published: 12/14/2016   |   Inventor(s): Nancy Bonini, David Meaney
Keywords(s):  
Category(s): Medical Devices, Research Tools & Reagents, Veterinary & Animal Health
Design of canine antibodies for targeted therapeutics
Methods for generating single chain variable region Fragments (scFvs) for use as targeting agents for the treatment of infectious, inflammatory and neoplastic diseases in dogsInventorNicola Mason (Mason Canine Cancer Immunotherapy Research) ProblemCancer is the leading cause of death in our current canine pet population. Previous studies have found...
Published: 7/12/2016   |   Inventor(s): Nicola Mason
Keywords(s):  
Category(s): Therapeutics & Vaccines, Diagnostics, Veterinary & Animal Health
Naturally derived vaccine adjuvant and immunostimulant for use in humans and animals
InventorDr. Carolina Lopez (http://www.lopezlab.org/)Brief DescriptionUnique RNA molecule derived from defective viral genomes containing potent immunostimulatory and adjuvant propertiesProblemThe vaccine industry is steadily moving away from live-attenuated and whole-pathogen products, mostly due to safety concerns. In fact, it is projected that b...
Published: 4/28/2016   |   Inventor(s): Carolina Lopez
Keywords(s):  
Category(s): Therapeutics & Vaccines, Research Tools & Reagents, Veterinary & Animal Health