Available Technologies

Browse Penn-owned technologies available for licensing.

HOME SEARCH RSS FEED

Agricultural formulation and transgenic methods for regulating crop yield

Description:

Phytohormone gibberellin controls onset of plant development and flower formation

 

Inventor

Doris Wagner, Professor of Biology

  

Technology Overview

The Wagner lab has uncovered dual opposite roles of the phytohormone gibberellin in the events that lead to formation of flowers, fruits, and seeds.  Elevated gibberellin promotes termination of the vegetative phase and triggers bolting, while reduced gibberellin triggers flower formation.  These two events are coupled in that gibberellin increases the expression of genes encoding transcription factors, including Squamosa promoter binding protein (SPL) and LEAFY, that promote the transition to inflorescence development.  Once these have accumulated, reducing gibberellin levels lead to upregulation of critical factors for making flowers such as APETALA1.  The researchers have shown that induction of a gibberellin catabolism enzyme, ELA1, to lower gibberellin levels, or of gibberellin insensitive versions of DELLA proteins, or application of paclobutrazol at the right time (after bolting and LEAFY/SPL accumulation) will trigger promote flower, fruit, and seed formation.  Properly timed lowering of gibberellin should be particularly useful to enhance yield in woody perennials (fruit trees etc.), but also likely in annual plants. 

Advantages

•       Optimizes crop yield over existing formulations and techniques

 

Applications

•       Increase seed yield by adjusting gibberellin metabolism

•       Optimize pollination

•       Control onset of flower, fruit, and seed formation

•       Biofuel production

 

 

Stage of Development

•       Reduction to practice

 

Intellectual Property

PCT pending (WO2015168124 A1)

 

Reference Media

Yamaguchi N et al.  Science, 2014, 344(638), p. 638-641.

 

Desired partnerships

• License

Co-development

 

 

Download PDF

 

Docket #  14-7118 


Patent Information:
For Information, Contact:
Joshua Jeanson
Associate Director, SEAS/SAS Licensing Group
University of Pennsylvania
jeanson@upenn.edu
Inventors:
Doris Wagner
Keywords: