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SLOW RELEASE HYDROGEL SYSTEM FOR DELIVERING THERAPEUTICS TO THE MIDDLE AND INNER EAR

Description:

The invention comprises a slow release hydrogel formulation for sustained, localized and controlled delivery of therapeutics to the middle and/or inner ear.  Treatment of middle and inner ear pathologies is a very large area of unmet need, as most current strategies fail to deliver a high-level and localized sustained dose of a therapeutic to the middle and/or inner ear.  This technology, which overcomes the localized high-dose delivery hurdle, has the potential of being useful in the treatment of middle ear and inner ear pathologies including Meniere’s disease.  The hydrogel slowly degrades over time as it delivers its therapeutic cargo, and it has also has been developed to allow it to be quickly degraded and washed out in emergency situations through the application of an exogenously applied enzyme.  We would be excited to explore opportunities for co-development or direct licensing of this hydrogel drug delivery technology with all interested parties.    

IP Status:
Pending US rights

References:
J Control Release. 2013 Mar 28;166(3):268-76.

Docket #U4595


Patent Information:
For Information, Contact:
Neal Lemon
Associate Director, PSOM Licensing Group
University of Pennsylvania
nlemon@upenn.edu
Inventors:
Bert O'malley
Daqing Li
Keywords: