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LASER TISSUE SOLDER FOR RAPID, WATERTIGHT AND PRESSURE-BEARING SURGICAL CLOSURES

Description:
Producing watertight, strong, high burst-strength surgical wound closures in internal organs and tissues has long been a challenge faced by surgeons in many disciplines.  This invention comprises a chitosan-based tissue solder formulation that is applied as a gel and hardened quickly in place using a surgical laser without damaging / burning surrounding tissues.  Using their optimized tissue solder formulation, the Penn scientists have demonstrated high burst strength, watertight and air-tight wound closure in various tissues as well as efficient healing of the wound following tissue welding in preclinical animal models.  This technology is well positioned to provide surgeons with a tool to rapidly, reproducibly and strongly close large openings produced during surgery and other wounds, where it is critical to achieve a watertight and high burst-strength closure but where suturing is not an option.  We would be excited to explore opportunities for co-development or direct licensing with parties interested in commercializing this technology.    

IP Status:
Pending US rights
Pending AU, CA, EU, and IN rights

References:
Am J Rhinol Allergy. 2013 Mar-Apr;27(2):148-50.
Arch Facial Plast Surg. 2012 Jan-Feb;14(1):52-8.
Am J Rhinol Allergy. 2010 May-Jun;24(3):244-6.
Chest. 2010 Aug;138(2):345-9.
Am J Rhinol. 2008 Nov-Dec;22(6):625-8.
Otolaryngol Head Neck Surg. 2008 Nov;139(5):713-7.
Otolaryngol Head Neck Surg. 2007 Nov;137(5):810-4.


Patent Information:
Category(s):
Medical Devices
For Information, Contact:
Jeffrey James
TLO
University of Pennsylvania
215-746-7041
jeffja@upenn.edu
Inventors:
Ben Bleier
Noam Cohen
James Palmer
Keywords: