Safe, minimally-invasive, non-viral delivery of nucleic acid into the central nervous system (CNS) to protect cells from ischemic or traumatic injury
Problem:
Gene therapy has significant potential to advance clinical medicine. However, long-term gene expression delivered by viral modes may contribute to risks, and the duration of expression must be matched with the appropriate indication. Transient expression to address acute indications, such as neuroprotection after ischemic or traumatic injury, could significantly aid in recovery and prevent long-term effects.
Solution:
Dr. Hecker has developed a non-viral cationic lipid-based delivery system to address transient gene therapy needs. The application is minimally invasive, through injection into the CNS, and is highly effective in transfection of both neuronal and non-neuronal cells.
Advantages:
- Low immunogenicity
- Easy preparation
- No limitations on vector size
Case ID:
P3141-tpNCS
Web Published:
11/27/2018
Patent Information:
App Type |
Country |
Serial No. |
Patent No. |
File Date |
Issued Date |
Expire Date |