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Method to Determine Risk of Preterm Birth

Description:

 

Problem

 

Preterm birth accounts for ~12% of all births in the US and costs an estimated $26.2 billion each year.  Current methods for identifying patients at risk for preterm birth rely on socioeconomic, behavioral, and clinical factors such as age, tobacco use, or previous preterm birth, respectively.  Although there are numerous factors known to be associated with preterm birth, it remains difficult to accurately predict patients at risk.   

 

Solution

A large prospective study of pregnant women led by Dr. Elovitz confirmed the association of cervicovaginal bacteria with preterm birth risk.  Specific bacteria were found to be associated with either an increased or decreased risk of preterm birth.  These results indicate that identification of bacteria could be used as a method for determining a patient’s risk of preterm birth.

 

 

Advantages

• Non-invasive

• Early detection

• Clinically validated

 

Application

• Identification of risk of preterm birth

 

Stage of Development

Prospective clinical study complete

  

Intellectual Property

WO 2018129043A1 

 

Reference Media

March of Dimes, January 23, 2017

Medscape, February 6, 2017

Elovitz MA et al.  Am J Obstet Gynecol, 216 (1) – S8-S9, 2017.

Downes KL et al. Am J Obstet Gynecol, 216 (1) – S218, 2017.

 

Desired partnerships

• License

Co-development

 

Docket # 17-8103 

 

Download pdf


Patent Information:
Category(s):
Diagnostics
For Information, Contact:
Viviane Martin
Director, PSOM Licensing Group
University of Pennsylvania
215-746-4275
martinv@upenn.edu
Inventors:
Michal Elovitz
Jacques Ravel
Pawel Gajer
Keywords: