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anti-GPVI (Mouse)

Description:
Monoclonal (IgG)

Clone: Hy101 (or 11A12)
Applications: Flow cytometry, WB, binding inhibition in vitro
Species Reactivity: Human
Alternative Names: GP 6
Immunogen: GPVI R272L expressed on 3T3 cells

Relevant Publications:

  • [Flow cytometry, WB] - Chen H, Locke D, Liu Y, Liu C, Kahn ML. The platelet receptor GPVI mediates both adhesion and signaling responses to collagen in a receptor density-dependent fashion. J Biol Chem. 2002 Jan 25;277(4):3011-9 [Pubmed: 11723134]
  • [binding inhibition in vitro] - Sarratt KL, Chen H, Zutter MM, Santoro SA, Hammer DA, Kahn ML. GPVI and alpha2beta1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow. Blood. 2005 Aug 15;106(4):1268-77. [Pubmed: 15886326]
  • [Flow cytometry] - Hermans C, Wittevrongel C, Thys C, Smethurst PA, Van Geet C, Freson K. A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder. J Thromb Haemost. 2009 Aug;7(8):1356-63 [Pubmed: 19552682]

Tech-ID: N2626


Patent Information:
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Reagents: Antibodies