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anti-SMN (Mouse)

Description:
Monoclonal (IgG1)

Clone: 2B1
Applications: ICC, IP, WB
Species Reactivity: Human
Alternative Names: gemin 1, SMN1
Immunogen: Anti-SMN antibody (2B1) was prepared by immunizing A/J mice with His6- tagged SMN protein (human) purified from Ni+ chelation. Hybridoma production, screening and ascites fluid production were then performed.

Relevant Publications:

  • [ICC, IP, WB] - Liu Q, Dreyfuss G., A novel nuclear structure containing the survival of motor neurons protein., EMBO J. 1996 Jul 15;15(14):3555-65. [Pubmed: 8670859]
  • [ICC, IP, WB] - Battle DJ, Kasim M, Wang J, Dreyfuss G., SMN-independent subunits of the SMN complex. Identification of a small nuclear ribonucleoprotein assembly intermediate., J Biol Chem. 2007 Sep 21;282(38):27953-9. Epub 2007 Jul 19. [Pubmed: 17640873]
  • [ICC, IP] - Giesemann T, Rathke-Hartlieb S, Rothkegel M, Bartsch JW, Buchmeier S, Jockusch BM, Jockusch H., A role for polyproline motifs in the spinal muscular atrophy protein SMN?, J Biol Chem. 1999 Dec 31;274(53):37908-14. [Pubmed: 10608857]

Tech-ID: U4740


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Reagents: Antibodies