Bilayer Solid-State Nanopores for the Tracking, Filtering and Guiding of DNA
A bilayered solid-state nanopore material that senses and guides DNA and other biomolecules into homogeneous configurations. Problem: Current methods of DNA sensing and sequencing typically involve short read lengths, chemical labeling, labor-intensive sample preparation, and lack of portability. To minimize these issues during DNA sequencing, protein-based...Researcher(s):
Yung-Chien Chou, Marija Drndic, Chih-Yuan Lin, Dimitrios MonosKeyword(s):
NanotechnologySolid-state nanopore membranes for DNA detection and sequencing
A technology portfolio comprising fabrication and detection methods for improved DNA sequencing using nanoporous membranes. Technology Overview: This technology portfolio consists of fabrication methods for generating ultra-thin Silicon Nitride (SiN) membranes and ultra- low capacity, glass supported dielectric membranes for DNA sequencing....Researcher(s):
Marija DrndicSolid state nanopore DNA sequencing
Problem: Existing sequencing processes require DNA to be copied millions of times and labelled with fluorescent tags. This procedure can require eight days of processing time at a cost of thousands of dollars. The slow and expensive process presents a barrier to screening patients’ genomes and inhibits the rise of personalized medicine. Solution:...Researcher(s):
Marija DrndicKeyword(s):
NanotechnologyGraphene nanopore devices to monitor DNA translocations
Technology Overview: This invention is a fabrication method to generate a 1−5 nm thick graphene membrane on top of a silicon nitride window. The membrane is then drilled with transmission electron beam ablation lithography to create nanopores that are 5 to 10 nm in diameter. Graphene nanopore devices offer better performance than other methods...Researcher(s):
Marija Drndic
- ‹
- 1
- ›