Search Penn Technologies & Inventors

Showing results for 4 inventions

Sort by:
Keywords
Researchers
  1. Bilayer Solid-State Nanopores for the Tracking, Filtering and Guiding of DNA

    A bilayered solid-state nanopore material that senses and guides DNA and other biomolecules into homogeneous configurations. Problem: Current methods of DNA sensing and sequencing typically involve short read lengths, chemical labeling, labor-intensive sample preparation, and lack of portability. To minimize these issues during DNA sequencing, protein-based...
  2. Solid-state nanopore membranes for DNA detection and sequencing

    A technology portfolio comprising fabrication and detection methods for improved DNA sequencing using nanoporous membranes. Technology Overview: This technology portfolio consists of fabrication methods for generating ultra-thin Silicon Nitride (SiN) membranes and ultra- low capacity, glass supported dielectric membranes for DNA sequencing....

    Researcher(s):

    Marija Drndic
  3. Solid state nanopore DNA sequencing

    Problem: Existing sequencing processes require DNA to be copied millions of times and labelled with fluorescent tags. This procedure can require eight days of processing time at a cost of thousands of dollars. The slow and expensive process presents a barrier to screening patients’ genomes and inhibits the rise of personalized medicine. Solution:...

    Researcher(s):

    Marija Drndic

    Keyword(s):

    Nanotechnology
  4. Graphene nanopore devices to monitor DNA translocations

    Technology Overview: This invention is a fabrication method to generate a 1−5 nm thick graphene membrane on top of a silicon nitride window. The membrane is then drilled with transmission electron beam ablation lithography to create nanopores that are 5 to 10 nm in diameter. Graphene nanopore devices offer better performance than other methods...

    Researcher(s):

    Marija Drndic
  • 1