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Enhancing polymer stability via extreme nanoconfinement
Technology Overview: Polymers are an important class of materials with applications in almost all aspects of life. Based on the chemicals used, a polymeric material can have a wide range of properties as well as costs. High thermal or chemical stability is highly desired in: Coatings Organic electronics Flame-retardant materials Chemical safety...
Published: 4/28/2020   |   Inventor(s): Zahra Fakhraai, Daeyeon Lee, Haonan Wang, Jyo Lyn Hor
Keywords(s):  
Category(s): Materials
Fluorinated building blocks for organic synthesis and macromolecule synthesis
Synthesis of trifluoromethylated alkylboron compounds and incorporation into small molecules and macromolecules Problem: Fluorinated macromolecules are widely utilized in industry, with the most notable example being Teflon, or perfluorotetrafluoroethylene (PTFE). Additionally, methods for incorporating CF3 into small organic molecules are not...
Published: 3/20/2020   |   Inventor(s): Gary Molander
Keywords(s):  
Category(s): Chemical Processes and Synthesis, Materials, Research Tools & Reagents
Stabilized, shear-thinning hydrogels as scaffolds for drug delivery and regenerative medicine
Secondary crosslinking of injectable shear-thinning hydrogels to enhance mechanics and stability Problem: Hydrogels are crosslinked polymers that are used in biomedical applications for culturing cells in vitro or for the delivery of cells or therapeutic molecules in vivo. Injectable hydrogels may be introduced into patients in a minimally invasive...
Published: 3/20/2020   |   Inventor(s): Jason Burdick
Keywords(s): Bioengineering
Category(s): Materials
Nanocrystal circuits for flexible electronics
New fabrication techniques for CdSe QD FETs Problem: Many researchers are attempting to create flexible electronics, which could have applications for new mobile and wearable devices. However, traditional semiconductor materials are not flexible, so new materials and fabrication techniques are needed to make flexible electronics possible. Solution:...
Published: 3/20/2020   |   Inventor(s): Cherie Kagan
Keywords(s):  
Category(s): Hardware & Circuits & Sensors, Materials
Reusable silicon-based cross-coupling agents for the production of natural products, pharmaceuticals, and other organic materials
Cross-coupling reactions without the generation of waste products Problem: Catalytic carbon-carbon bond formation based on cross-coupling reactions (CCRs) plays a central role in the production of natural products, pharmaceuticals, agrochemicals, and organic materials. Coupling reactions with organometallic reagents and organic halides facilitate...
Published: 3/20/2020   |   Inventor(s): Amos Smith
Keywords(s):  
Category(s): Chemical Processes and Synthesis, Materials, Research Tools & Reagents, Therapeutics & Vaccines
Diamond-like carbon coating for Heat Assisted Magnetic Recording (HAMR)
New materials to make advanced recording technology possible Problem: Heat-Assisted Magnetic Recording (HAMR) could provide hard drive storage densities in the TB/in^2 range, as compared to today’s GB/in^2 capability. HAMR operates by heating the disk with a laser, which momentarily changes the storage medium’s magnetic coercivity,...
Published: 3/20/2020   |   Inventor(s): Robert Carpick
Keywords(s):  
Category(s): IT & Communication & Networking, Materials
Visible light absorbing ferroelectric materials for photovoltaics
Technology Overview: The invention covers the bandgap engineering strategy wherein two different transition-metal cations located on the perovskite B-site create ferroelectric perovskites with low bandgaps, with one cation driving ferroelectricity and the other giving a bandgap in the visible range. The solid solutions were synthesized by standard...
Published: 3/19/2020   |   Inventor(s): Andrew Rappe
Keywords(s):  
Category(s): Materials
A novel isostere to replace the carboxylic acid functional group in pharmaceuticals and other compounds
Cycloalkyl-dione derivatives with improved pharmacokinetic and toxicological properties for drug design Problem: Isosteric replacement of a specific group of atoms with a moiety with similar physicochemical properties is a strategy employed by medicinal chemists to improve the properties of biologically active compounds. For example, carboxylic...
Published: 3/19/2020   |   Inventor(s): Amos Smith, Donna Huryn, Carlo Ballatore, Virginia Lee, John Trojanowski
Keywords(s):  
Category(s): Chemical Processes and Synthesis, Materials, Therapeutics & Vaccines
Fabricating specialized oleosins: From surfactants to drug delivery to imaging
Technology Overview: The Hammer and Lee Labs have developed a method to produce oleosins and functionalized oleosins for a wide variety of applications from surfactants to a drug delivery vehicle to cancer cells. E. Coli can be can be transformed to fabricate oleosin or oleosin with additional molecules, including antibodies and GFP. Problem:...
Published: 3/18/2020   |   Inventor(s): Daniel Hammer, Daeyeon Lee
Keywords(s): Nanotechnology
Category(s): Materials, Imaging
Graphene metamaterials
Advanced optical materials made possible using graphene Problem: Plasmonic nanostructures are used to create metamaterials with unusual optical properties. Most metamaterials to date have been constructed using noble metals, however, these metals have inherent losses that degrade the metamaterial's optical properties. Graphene does not...
Published: 3/18/2020   |   Inventor(s): Nader Engheta
Keywords(s):  
Category(s): Materials
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