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One step N-terminal tagging of endogenous proteins for therapeutic delivery, diagnostics, and in vivo imaging
N-Terminal protein modification using adenosine substrates and aminoacyl transferase Problem: The conjugation of synthetic molecules to the termini of proteins with minimal effects on protein folding and function is an active area of biochemical research. Previous N-terminal protein modification methods suffer from side reaction products, incomplete...
Published: 3/19/2020   |   Inventor(s): E. James Petersson, Alan Saghatelian
Keywords(s):  
Category(s): Chemical Processes and Synthesis, Research Tools & Reagents, Diagnostics, Therapeutics & Vaccines