Engineered Fanzor2 (Fz2) nucleases with enhanced genome editing activity in mammalian cells and demonstrated genome editing in mice.
A low-cost, biodegradable, passive environmental sensor using metasurfaces and polymers to optically respond to changes in environment (humidity, volatile compounds, temperature).
A high throughput, model-guided tool that prioritizes candidate amino acid substitutions for protein optimization under sparse data conditions.
A modular rehabilitation robot system reconfigures mechanical modules into multiple upper-limb therapy setups for unilateral and bilateral shoulder and elbow training.
A modular truss system uses concentric spherical joint linkages and reconfigurable members to enable structural sections to be added, removed, expanded, or collapsed.
Automated fluorescence and optical density measurements with simultaneous optogenetics stimulation in 96-well microwell plates.
Enhancing dendrimer synthesis efficiency with pseudosymmetrization of polylysines.
Conjugating anti-T cell targeting domains onto anti-tumor autoantibodies to convert them into highly specific T cell-redirecting antibodies capable of increasing immune cell recruitment to tumor tissue.
An all-aqueous microcapsule platform forms complexation films around cargo for biocompatible encapsulation without an oil phase.
Magnetic pore filters in microfluidic devices enable capture, release, and analysis of magnetically tagged particles, including cells and exosomes.