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Therapeutic antibodies against pathological tau proteins for the treatment of Alzheimer’s Disease (AD)

Two novel monoclonal antibodies were discovered that target pathological conformations of the tau protein. The antibodies were shown in vitro and in vivo to inhibit the spread of pathological tau protein aggregates, which is one of the defining characteristics of AD.

Published: 10/16/2023
Inventor(s):
Garrett Gibbons, Virginia Lee, Dawn Riddle, John Trojanowski
Keywords(s):
Antibody, Neurodegenerative Diseases
Category(s):
Technology Classifications > Therapeutics