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Search Results - donald siegel

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Human monoclonal autoantibodies to ADAMTS13 and uses thereof
Human anti-ADAMTS13 antibodies cloned from patients with acquired thrombotic thromobocytopenia purpura (TTP) for use in targeted therapies, and generation of animal models that recapitulate pathologic features of TPP. Technology Overview: Thrombotic thrombocytopenic purpura (TTP) is a rare but life-threatening blood disorder where blood clots...
Published: 1/28/2020   |   Inventor(s): Donald Siegel, Eric Ostertag, X. Long Zheng
Keywords(s):  
Category(s): Diagnostics, Therapeutics & Vaccines, Research Tools & Reagents
Recombinant antibody fragments for targeted treatment of autoimmune skin disease
Recombinant antibodies for diagnosis, treatment, and targeted drug delivery in skin disease. Technology Overview: Bullous pemphigoid (BP) is an autoantibody-mediated blistering skin disease in which the epidermal cells lose adhesion to the basement membrane. Patients feature circulating and tissue-bound autoantibodies that target two basement...
Published: 11/15/2019   |   Inventor(s): Matthias Hammers, Donald Siegel, John Stanley
Keywords(s):  
Category(s): Diagnostics, Therapeutics & Vaccines