Search Results - drew+weissman

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Adjuvanted Lipid Nanoparticles (LNPs) Enhance Protective Immunity Imparted by SARS-CoV-2 mRNA Vaccine

A lipid nanoparticle formulation that elicits a strong innate immune response for improved vaccine protection

Published: 10/1/2024
Inventor(s):
Michael Mitchell, Xuexiang Han, Drew Weissman, Mohamad Alameh
Keywords(s):
Bioengineering, COVID-19, Drug Delivery, Immunology, Infectious Disease, Nanotechnology
Category(s):
Technology Classifications > Materials, Technology Classifications > Vaccines

Targeted Organ or Multiple Organ Delivery of mRNA with Ionizable Amphiphilic Janus Dendrimers

A library of easily synthesized ionizable amphiphilic Janus dendrimer (IAJD) compounds that deliver mRNA either to targeted organs or multiple organs, depending on the IAJD design.

Published: 7/23/2024
Inventor(s):
Virgil Percec, Drew Weissman, Juncheng (Luke) Lu, Elena Atochina-Vasserman, Devendra Maurya, Dipankar Sahoo
Keywords(s):
Drug Delivery, Platform Technology
Category(s):
Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Vaccines

Immune Modulator Encoded Lipid Nanoparticle Formulation Improves T Cell Response to Vaccines

Researchers developed an LNP-mRNA-based vaccine that encodes different cytokine mRNAs, as a method to enhance CD8+ T cell responses and memory formation.

Published: 7/2/2024
Inventor(s):
Christopher Hunter, Drew Weissman, Mohamad Alameh, Emily Aunins, Anthony Phan
Keywords(s):
Bioengineering, Drug Delivery, Immunology, Immunoncology, Immunotherapy, Infectious Disease, Nanotechnology
Category(s):
Technology Classifications > Therapeutics, Technology Classifications > Vaccines