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Search Results - jacob brenner

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Targeted drug delivery using red-blood cells for transport
Platform technology for targeted drug delivery using red blood cells for transport. Problem: Drug delivery can often result in up to 99% of the drug being delivered to off-target organs. This can lead to side-effects and toxicities. Current methods that bind drugs to red-blood cells for transport can require modifying the structure of the red...
Published: 6/23/2020   |   Inventor(s): Laura Ferguson, Elizabeth Hood, Carlos Villa, Jacob Brenner, Vladimir Muzykantov
Keywords(s): Acute Lung Injury, Cardiovascular, COVID-19, Drug Delivery, Nanotechnology, Respiratory
Category(s): Therapeutics & Vaccines
Improving drug delivery using red blood cell hitchhiking
Problem: A major challenge in drug delivery is ensuring that the drug reaches the target organ at a concentration sufficient to treat the disease. This is particularly problematic for acute illnesses of the vasculature, such as acute respiratory distress syndrome (ARDS), ischemic stroke, and myocardial infarction. In these diseases, patients are often...
Published: 2/13/2020   |   Inventor(s): Jacob Brenner, Vladimir Muzykantov
Keywords(s): COVID-19
Category(s): Therapeutics & Vaccines