Search Results - jacob brenner

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Targeted drug delivery using red-blood cells for transport

Platform technology for targeted drug delivery using red blood cells for transport. Problem: Drug delivery can often result in up to 99% of the drug being delivered to off-target organs. This can lead to side-effects and toxicities. Current methods that bind drugs to red-blood cells for transport can require modifying the structure of the red...

Published: 6/23/2020 | Inventor(s): Laura Ferguson, Elizabeth Hood, Carlos Villa, Jacob Brenner, Vladimir Muzykantov

Keywords(s): Acute Lung Injury, Cardiovascular, COVID-19, Drug Delivery, Nanotechnology, Respiratory

Category(s): Therapeutics & Vaccines

Improving drug delivery using red blood cell hitchhiking

Problem: A major challenge in drug delivery is ensuring that the drug reaches the target organ at a concentration sufficient to treat the disease. This is particularly problematic for acute illnesses of the vasculature, such as acute respiratory distress syndrome (ARDS), ischemic stroke, and myocardial infarction. In these diseases, patients are often...

Published: 2/13/2020 | Inventor(s): Jacob Brenner, Vladimir Muzykantov

Keywords(s): COVID-19

Category(s): Therapeutics & Vaccines

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