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Histone deacetylase and DNA methyltransferase inhibitors for preventative cardiac care and ischemic injury treatment

HDAC and DNMT Inhibitors such as Trichostatin A (TSA) and 5-aza-cytidine are preventative therapies and reduce myocardial infarct volume following cardiac events Technology Overview: Every 40 seconds, someone in the United States has a heart attack. Although several therapeutic options for heart attack recovery exist, ischemic injuries are responsible...

Published: 2/3/2021

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Pharmaceutical therapeutic for the treatment of respiratory diseases

Histone deacetylase (HDAC) inhibitors such as Trichostatin A to treat bronchoconstrictive diseases including asthma and chronic obstructive pulmonary disorder (COPD) Technology Overview: Asthma and COPD are diseases of variable airflow obstruction affecting more than 40 million Americans. Although some patients respond to conventional therapies,...

Published: 11/14/2019

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