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Immunotoxin Therapeutic Targets Epithelial Derived Cancers
Immunotoxin chimeras of DNaseI and cytolethal distending toxin (CdtB subunit) are an effective therapeutic against epithelial tumors. Technology Overview: Immortalized epithelioid cell lines are sensitive to CdtB, whereas cells of mesenchymal, or ectomesenchymal origin are relatively resistant. Unique chimeras of the cdtB gene and human type I...
Published: 11/27/2018   |   Inventor(s): Joseph Dirienzo
Keywords(s): Immunotherapy, Oncology
Category(s): Therapeutics & Vaccines