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Device for MRI Scanner Intra-Bore Disinfection
Magnetic field-safe device for rapid disinfection of MRI bore and other types of scanners (CT, PET, PET-MR, SPECT) that is effective against COVID19, MRSA and other pathogens.</rss.brief Problem: With the advent of COVID-19, renewed emphasis has been placed on disinfecting surfaces in the medical environment. Disinfecting the MRI scanner bore...
Published: 6/23/2020   |   Inventor(s): Norman Butler, James Pilla, Terence Gade, Gabor Mizsei
Keywords(s): Antibacterial, Antifungal, Antiviral, COVID-19
Category(s): Medical Devices, Hardware & Circuits & Sensors
Functional nerve guidance conduit for the rapid treatment of peripheral nerve injuries
A collagen-based nerve guidance conduit containing functional Schwann cell precursor-like cells derived from stem cells for the rapid treatment of peripheral nerve injuries. Technology Overview: A peripheral nerve injury (PNI) occurs in approximately 3% of all trauma patients. While treatment options for PNIs have improved with advances in microsurgical...
Published: 5/5/2020   |   Inventor(s): Anh Le, Qunzhou Zhang
Keywords(s):  
Category(s): Medical Devices, Therapeutics & Vaccines
Virtual reality for low vision patients
Problem: Low vision is a significant public health problem affecting more than 3.5 million people in the US alone compromising an individuals’ sense of independence, ability to carry out daily life activities, and safety. Without retinal input, the downstream visual pathways also deteriorate. Thus, enhancement of the remaining visual function...
Published: 4/1/2020   |   Inventor(s): Jean Bennett, Tomas Aleman, Michael Stauffer, Mikhail Lipin, Manzar Ashtari, Ranjoo Prasad
Keywords(s):  
Category(s): Medical Devices, Digital Health, Software & Data & Algorithms & Apps
Electrodes for long term in-vivo implantation and in-vitro use
Problem: Implantable devices for use in the body of a subject, such as neural prosthetic systems, have had limited success due to the challenges presented by the environment the devices are exposed to. Long-term interaction with the implantable device and the body takes a toll on these implantable devices. Impedance degradation, scar tissue formation,...
Published: 3/23/2020   |   Inventor(s): Brian Litt
Keywords(s):  
Category(s): Medical Devices
New device for aortic repair and replacement
Problem: Professors from Penn Cardiothoracic Surgery have designed a single device that is able to replace the aortic valve and repair the ascending aorta in one procedure. Patients with only aortic valve disease often undergo a minimally-invasive surgery called transcatheter aortic valve Implantation/replacement (TAVI). But for patients who also...
Published: 3/20/2020   |   Inventor(s): Bartosz Rylski, Karianna Milewski, Joseph Bavaria
Keywords(s):  
Category(s): Medical Devices
Hyperpolarized gas delivery to subject in MRI scanner for enhanced pulmonary diagnostics and disease progression monitoring
Device for the optimal mixing and delivery of MRI gaseous contrast agents Problem: Gaseous contrast agents, and more specifically, hyperpolarized (HP) noble gases, such as helium-3 and xenon-129, are used for investigational imaging of respiratory gas in lungs by MRI for the purpose of assessing regional lung function. The ultimate goals of such...
Published: 3/20/2020   |   Inventor(s): Kiarash Emami, Stephen Kadlecek
Keywords(s):  
Category(s): Diagnostics, Imaging, Medical Devices
High spatial and temporal resolution mapping of brain activity using flexible multiplexed electrode arrays with long term stability and safety
Flexible foldable actively multiplexed high density electrode array for mapping brain activity in-vivo Problem: Electrode arrays for recording and stimulating the brain are used throughout clinical medicine and basic neuroscience research, but are unable to sample large areas of the brain while maintaining high spatial resolution because of the...
Published: 3/19/2020   |   Inventor(s): Brian Litt
Keywords(s): Neurodegenerative Diseases
Category(s): Diagnostics, Medical Devices
A disposable self-heating cartridge for point-of-care molecular diagnostics
A water-activated, self-heating, instrument-free microfluidic diagnostic cartridge Problem: Many molecular diagnostic devices require elevated temperatures to carry out biochemical reactions, such as those needed for nucleic acid amplification, including loop-mediated isothermal amplification (LAMP). The temperature is typically regulated with external...
Published: 3/19/2020   |   Inventor(s): Changchun Liu, Haim Bau
Keywords(s):  
Category(s): Diagnostics, Medical Devices, Research Tools & Reagents
A membrane-based, high-efficiency microfluidic debubbler for point-of-care devices
Problem: Microfluidic devices often suffer from unwanted bubbles inside a channel, resulting in obstructed fluidic paths, lower reaction efficiency, detection distortion, and interference with bead array-based assays. Existing active debubblers that use pneumatics or vacuum to trap and dissipate bubbles require an external vacuum source, preventing...
Published: 3/19/2020   |   Inventor(s): Haim Bau, Changchun Liu
Keywords(s):  
Category(s): Diagnostics, Medical Devices, Research Tools & Reagents
Antimicrobial coating for medical device, biosensor, nanofluidic, and drug delivery applications
Multifunctional, chemically modified chitosan surfaces and charged polymer brushes with protection against microbes and changes in pH Problem: Chitosan, a cationic polysaccharide, is a biocompatible and biodegradable coating material. While chitosan has been used for drug delivery, wound dressings, and tissue materials, this material has not been...
Published: 3/18/2020   |   Inventor(s): Russell Composto, David Eckmann, Noreen Hickok
Keywords(s):  
Category(s): Chemical Processes and Synthesis, Medical Devices
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