Search Results - platform+technology

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Augmented Reality Interface for Radiation-Free Screw Insertion during Intramedullary Nail Insertion for Long Bone Fractures

The NailedIt Augmented Reality (AR) Surgical Navigation System, comprised of a Windows-based desktop application, augmented reality headsets (HMDs) worn by surgeons, handheld mobile devices supporting remote viewing and surgical site annotation, and spatially tracked medical devices and instruments, assists and guides surgeons while they perform orthopedic surgical tasks using an immersive augmented reality user interface.

Published: 4/10/2024
Inventor(s):
Thomas Schaer, Stephen Lane, Samir Mehta
Keywords(s):
Augmented Reality (AR) & Virtual Reality (VR), Orthopedics, Platform Technology, Software, Surgery
Category(s):
Technology Classifications > Medical Devices

Ultrasensitive, High-Throughput, Single-Scale Detection of Extracellular Vesicles

An optofluidic platform to detect extracellular vesicles (EVs) at the single-particle level by parallelizing droplet generation and analysis of EVs.

Published: 2/26/2024
Inventor(s):
David Issadore, Zijian Yang
Keywords(s):
Bioengineering, Microfluidics, Optics & Photonics , Platform Technology
Category(s):
Technology Classifications > Diagnostics, Technology Classifications > Research Tools & Reagents, Technology Classifications > Testing & Measurement

Human-AI Hybrid Intelligence Model to Accurately Recognize and Segment Organs on Medical Scans 70% Faster Than Physicians

AAR-DL (Automatic Anatomy Recognition – Deep Learning) is a hybrid intelligence recognition and delineation segmentation model that outputs automatically delineated organs in medical images by combining natural intelligence’s (i.e., human knowledge’s) and artificial intelligence's strengths to map organs and their boundaries in the given images.

Published: 2/2/2024
Inventor(s):
Jayaram Udupa, Tiange Liu, Dewey Odhner, Chao Jin, Yubing Tong, Drew Torigian
Keywords(s):
Artificial Intelligence (AI) & Machine Learning, Data Science, Healthcare IT, Oncology, Platform Technology, Radiology, Software
Category(s):
Technology Classifications > Computer Information Systems, Technology Classifications > Diagnostics, Technology Classifications > Imaging

High-Throughput and Independent Temperature Regulation In Biological Samples

A device that provides independent thermal regulation for biological samples in a 96-well microwell plate.

Published: 12/1/2023
Inventor(s):
Lukasz Bugaj, Brian Chow, William Benman, Zikang (Dennis) Huang
Keywords(s):
Bioengineering, Platform Technology
Category(s):
Technology Classifications > Hardware & Components, Technology Classifications > Research Tools & Reagents, Technology Classifications > Testing & Measurement

Stable Biological Membrane Mimetic For Enhanced Protein Recruitment

Synthetic biological alternative to natural lipids for conjugation with nitrilotriacetic acid (NTA) for enhanced His-tagged protein interaction and long-term stability.

Published: 10/16/2023
Inventor(s):
Virgil Percec, Qi Xiao, Matthew Good
Keywords(s):
Bioengineering, Platform Technology
Category(s):
Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Research Tools & Reagents

Double Digital Assay for Isolation and Analysis of Single Extracellular Vesicles for Early Detection of Disease Biomarkers Including Cancer

An ultrasensitive diagnostic tool that isolates single extracellular vesicles (EVs) and measures their contents to single molecule resolution.

Published: 10/16/2023
Inventor(s):
Jina Ko, David Reynolds, Menghan Pan
Keywords(s):
Bioengineering, Infectious Disease, Microfluidics, Oncology, Platform Technology
Category(s):
Technology Classifications > Diagnostics, Technology Classifications > Digital Health, Technology Classifications > Research Tools & Reagents, Technology Classifications > Hardware & Components, Technology Classifications > Testing & Measurement

RGD Peptide-Based Lipids For Targeted mRNA Delivery and Gene Editing Applications

A combinatorial library of RGD peptide (arginine-glycine-aspartic acid)-based lipids designed to formulate lipid nanoparticles for targeted mRNA delivery to the liver and the spleen.

Published: 2/7/2024
Inventor(s):
Michael Mitchell, Lulu Xue, Jingya Qin
Keywords(s):
Bioengineering, Drug Delivery, Gene Editing, Oncology, Platform Technology
Category(s):
Technology Classifications > Therapeutics, Technology Classifications > Vaccines

Ionizable Lipid Nanoparticles For In Vivo mRNA Delivery To The Placenta During Pregnancy

Lipid nanoparticles for selective mRNA delivery to the placenta to treat pre-eclampsia, FGR, and other pregnancy-related disorders.

Published: 2/7/2024
Inventor(s):
Michael Mitchell, Kelsey Swingle
Keywords(s):
Bioengineering, Drug Delivery, Gene Therapy, Platform Technology, Women's Health
Category(s):
Technology Classifications > Therapeutics

Cholesterol Analogues Incorporated Into LNPs For Enhanced mRNA Delivery

Hydroxycholesterols are used to formulate lipid nanoparticles (LNPs) for enhanced mRNA delivery into T cells.

Published: 2/6/2024
Inventor(s):
Michael Mitchell, Margaret Billingsley, Savan Patel, Xuexiang Han, Hanwen Zhang
Keywords(s):
Bioengineering, Cell Therapy, Drug Delivery, Gene Editing, Gene Therapy, Genetic Disorders, Immunology, Immunoncology, Immunotherapy, Inflammation, Nanotechnology, Platform Technology
Category(s):
Technology Classifications > Therapeutics

Amniotic Fluid Stabilized Lipid Nanoparticles (LNPs) for In Utero Intra-Amniotic mRNA Delivery

Nanoparticles for potent encapsulation and delivery of therapeutic molecules for prenatal fetal therapy in the amniotic sac

Published: 2/7/2024
Inventor(s):
Michael Mitchell, Kelsey Swingle, Margaret Billingsley, William Peranteau
Keywords(s):
Bioengineering, Cell Therapy, Gene Editing, Gene Therapy, Genetic Disorders, Immunology, Nanotechnology, Orphan Disease, Platform Technology
Category(s):
Technology Classifications > Therapeutics
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