Search Results - satyamaheshwar+peddibhotla

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Therapeutic for Type 2 Diabetes and other obesity-related metabolic disorders

Obesity is associated with buildup of fat within the cells of the liver, heart, and skeletal muscle. Intracellular fat accumulation leads to impairment in the ability of these cells to absorb glucose from the blood in response to insulin, called insulin resistance. However, the linkage between intracellular fat accumulation and insulin resistance is poorly understood. This invention has defined the upstream connection between fat accumulation in muscle cells and insulin resistance defining  a new candidate target strategy for the treatment of obesity-related metabolic disorders. 

Published: 2/9/2024