A biocompatible hydrogel releases matrix metalloproteinase inhibitors when exposed to elevated protease activity in diseased tissue.
The technology provides astatine-211 labeled sigma-2 ligand compounds and compositions for cancer treatment, radiotherapy administration, and chemosensitization.
Safe, minimally-invasive, non-viral delivery of nucleic acid into the central nervous system (CNS) to protect cells from ischemic or traumatic injury
Iron oxide nanoparticle compositions disrupt biofilms, such as dental biofilms, and support oral disease prevention by combining catalytic nanoparticles with hydrogen peroxide.
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New compounds identified through high throughput screening which improve mitochondrial function of Friedreich ataxia cells.
Intranasal delivery of dantrolene nanoparticles can improve motor neuron function, muscle strength, and movement coordination and can offer therapeutic benefits for treatment of Amyotrophic Lateral Sclerosis (ASL).
Chimeric antigen receptor (CAR) T cell therapy targeting CA19-9, an antigen over-expressed in several cancers, including 80-90% of pancreatic cancers.
Targeted delivery of an anti-inflammatory cytokine to prevent heart failure after myocardial infarction.