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An Effective Method to Evaluate the Risk of Heart Failure with Preserved Ejection Fraction (HFpEF) Using Endotrophin (ProC6) Biomarkers.

Measuring endotrophin (ProC6) in plasma predicts the risk of death, heart failure admission, and composite cardiovascular events in HFpEF patients.

Published: 3/12/2024

A Precise, Analytical Model to Measure Visual Function and Monitor Retinal Disease

A model to estimate the change in photoreceptor outer segment length that occurs upon light stimulation – a biomarker of cone function in the retina.

Published: 3/6/2024

Ultrasensitive, High-Throughput, Single-Scale Detection of Extracellular Vesicles

An optofluidic platform to detect extracellular vesicles (EVs) at the single-particle level by parallelizing droplet generation and analysis of EVs.

Published: 2/26/2024

Human-AI Hybrid Intelligence Model to Accurately Recognize and Segment Organs on Medical Scans 70% Faster Than Physicians

AAR-DL (Automatic Anatomy Recognition – Deep Learning) is a hybrid intelligence recognition and delineation segmentation model that outputs automatically delineated organs in medical images by combining natural intelligence’s (i.e., human knowledge’s) and artificial intelligence's strengths to map organs and their boundaries in the given images.

Published: 2/2/2024

Nuclear Speckles Predict Patient Outcome and Therapy Response in Cancer

Nuclear speckles marker predicts cancer patients survival as well as response to therapy, particularly HIF2α inhibitors.

Published: 1/10/2024

Revolutionizing CT Imaging: Gold Nanoparticles with Biodegradable Polymer Encapsulation

Innovative CT contrast agent using biodegradable polymer-encapsulated gold nanoparticles for enhanced imaging and safe excretion.

Published: 2/12/2024

Mutant Cytosine Modifying Enzymes to Enhance Epigenetic or Base-Editing on Genomic DNA

Mutant TET enzymes that stall the oxidation reaction of 5-methylcytosine (5mC) at 5-hydroxymethylcytosine (5hmC), and AID/APOBEC enzymes with hyperactive deamination activity.

Published: 1/12/2024

Xenon Biosensors Improve Early Breast Cancer Detection

A nuclear magnetic resonance (NMR) based enzyme-detection system comprising xenon (129Xe) biosensors complexed with an enzyme-specific peptide substrate.

Published: 10/16/2023
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