Modified antimicrobial peptides with protein sequences for augmenting antimicrobial and antibiofilm properties.
Viral vector-mediated gene silencing of a novel short retinal isoform of Prolactin promotes photoreceptor survival.
Liver-targeted small RNA interference (RNAi) therapy to treat nonalcoholic fatty liver diseases (NAFLD), including nonalcoholic steatohepatitis (NASH).
Antimicrobial peptides computationally mined from the human proteome.
A class of pyrazole derivatives that inhibit palmitoyl-transferases, resulting in increasing cancer cell responsiveness to epidermal growth factor receptor inhibitor and KRas mutant lung cancer growth inhibition as a single agent.
Topical LSD1 inhibition can treat skin diseases that include cutaneous squamous cell carcinoma (cSCC), actinic keratoses, and viral warts.
A method of treating Fragile X syndrome by correcting the abnormal DNA clusters causing the characteristic symptoms.
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Non-replicating viral delivery of shVASH1 to treat heart failure.
Small molecule therapeutics that aid in clearing abnormal protein deposits observed in neurodegenerative diseases.