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Search Results - vladimir muzykantov

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Targeted drug delivery using red-blood cells for transport

Platform technology for targeted drug delivery using red blood cells for transport. Problem: Drug delivery can often result in up to 99% of the drug being delivered to off-target organs. This can lead to side-effects and toxicities. Current methods that bind drugs to red-blood cells for transport can require modifying the structure of the red blood...

Published: 6/23/2020

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Targeting drugs to circulating red blood cells

Problem: Annual incidence of venous thrombosis in the U.S. is 1 to 2 per 1000 adults. Roughly 33% of those presenting with a thrombotic event will have recurrence within 10 years. Thrombosis can cause tissue ischemia and damage leading to severe complications and possible mortality. Conditions associated with uncontrolled acute inflammation such...

Published: 3/9/2020

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Improving drug delivery using red blood cell hitchhiking

style> Problem: A major challenge in drug delivery is ensuring that the drug reaches the target organ at a concentration sufficient to treat the disease. This is particularly problematic for acute illnesses of the vasculature, such as acute respiratory distress syndrome (ARDS), ischemic stroke, and myocardial infarction. In these diseases, patients...

Published: 2/13/2020

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