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Transcriptome in vivo analysis (TIVA)
Transcriptome in vivo analysis (TIVA) is a novel platform that enables spatial and temporal analysis of the transcriptome in single or multiple cells from a heterogeneous population. TIVA can be combined with numerous in vivo and in vitro functional analysis techniques which are not supported by current RNA isolation methodologies.
Temporal RNA transcriptome analysis within a cell
Spatial RNA analysis within a cell (e.g. dendrites of neurons or apical region of a stromal cell)
Rapid RNA capture from individual cells within the same tissue
Analysis of RNA in cells that are connected or in communication with one another
Measurement of in vivo rates of RNA accumulation or degradation
Use with other in vivo techniques, such as live-imaging or electrophysiology.
Pending US rights
Lovatt, D. et al. Nat Methods. 2014 Feb;11(2):190-6
Docket # W5534
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