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Diagnostic and preventative implantable device with computer-brain interface for treatment of epilepsy.
One percent of the world’s population suffers from epilepsy. Aside from seizures’ debilitating effects, patients are confined by their unpredictability. Prevention is one way to decrease seizures, but measures usually focus on only a single parameter such as high-frequency oscillations.
Drug treatment or surgery is used to curb seizures. Implantable devices that detect and administer drugs are increasingly sought out as treatment options for epilepsy. However, these devices are limited; they only activate at the start of a seizure and deliver a uniform dose regardless of the seizure’s severity, which can result in a delay in treatment or over-medication.
To address the limitations of these devices, the Litt Lab combined a closed responsive system with an implantable device that uses multi-level, closed loops:
The data is collected rapidly and is of high spatial and temporal resolution. Use of biologically compatible components for the device ensures long term stability and safety.
Brian Litt, MD, Department of Neurology
Stage of Development:
Docket # N2412, N2413 + T4357