Search Results - aging

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Interoceptomimetics: Dietary Supplements to Enhance Exercise Motivation and Performance

Enhancing exercise performance by modulating the activity of motivation-generating brain regions via stimulation of cannabinoid (CB1) receptors of the enteric nervous system.

Published: 4/30/2026
Inventor(s):
Christoph Thaiss, John Nicholas Betley
Keywords(s):
Aging, Cardiovascular, Healthcare IT, Microbiome, Neurology, Obesity Metabolic Disease and Diabetes, Regenerative Medicine, Small Molecule
Category(s):
Technology Classifications > Food Science and Nutrition, Technology Classifications > Therapeutics

Pharmacological Treatment for Sleep Disorders Improving Sleep Quality & Architecture

Targeting Heat Shock Factor 1 (HSF1) via gene therapy or using pharmacological compounds targeting HSF1 (e.g. geranylgeranylacetone or macrocyclic peptides) can increase sleep stability, promote deeper sleep, reduce sleep fragmentation, and improve recovery from sleep loss.

Published: 4/16/2026
Inventor(s):
Akhilesh Basi Reddy, Shintaro Yamazaki
Keywords(s):
Aging, Drug Target, Gene Therapy, Neurodegenerative Diseases, Protein/Peptide (Non-Antibody), Small Molecule, Women's Health
Category(s):
Technology Classifications > Therapeutics

Intranasally-Delivered Therapy For The Treatment Of Depression And Dementia

Intranasal nasal dantrolene nanoparticles alone, or in combination with lithium, can provide protection against depression and dementia with minimal or no side effects.

Published: 6/10/2026
Inventor(s):
Huafeng Wei
Keywords(s):
Aging, Immunology, Immunoncology, Infectious Disease, Inflammation, Neurodegenerative Diseases
Category(s):
Technology Classifications > Therapeutics

Intranasal Dantrolene Nanoparticle Use For Treatment Of Alzheimer's Disease

Intranasal delivering of dantrolene nanoparticles could potentially be used to inhibit memory loss and reduce amyloid plaques in patients with Alzheimer's disease.

Published: 6/10/2026
Inventor(s):
Huafeng Wei, Qing Cheng Meng, Ge Liang, Maryellen Eckenhoff
Keywords(s):
Aging, COVID-19, Nanotechnology, Neurodegenerative Diseases
Category(s):
Technology Classifications > Animal Health, Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Food Science and Nutrition, Technology Classifications > Research Tools & Reagents, Technology Classifications > Therapeutics

Machine-Learning Foundation Model For The Early Detection Of Neurodegenerative Diseases

A machine learning technique that identifies biomarkers from neuroimaging data, allowing for identification and treatment of populations vulnerable to neurodegenerative diseases.

Published: 5/11/2026
Inventor(s):
Saurabh Sihag, Alejandro Ribeiro
Keywords(s):
Aging, Artificial Intelligence (AI) & Machine Learning, Neurodegenerative Diseases, Neurology, Platform Technology, Radiology
Category(s):
Technology Classifications > Diagnostics, Technology Classifications > Digital Health, Technology Classifications > Imaging

An Adaptive, Language-Agnostic, and Generalizable Method to Determine the Hearing Level and Speech Perception Abilities of a Patient

This hearing test is tuned to a patient’s hearing level and changes based on performance to accurately diagnose hearing ability

Published: 5/11/2026
Inventor(s):
Jason Brant, Tiffany Hwa
Keywords(s):
Aging, Neurodegenerative Diseases, Software, Surgery
Category(s):
Technology Classifications > Diagnostics, Technology Classifications > Testing & Measurement

Method for Creating Super Resolution Medical Images

The deep learning algorithm retrospectively improves the resolution of routine medical images (e.g., CT, MRI, etc.) without the need for increased radiation or scan time. 

Published: 1/15/2025
Inventor(s):
Chamith Rajapakse
Keywords(s):
Aging, Artificial Intelligence (AI) & Machine Learning, Cell Therapy, Orthopedics, Radiology, Software
Category(s):
Technology Classifications > Imaging

Novel Pyrimidine Derivatives to Treat Alzheimer’s Disease

Brain penetrating compounds as promising therapeutics for treatment of neurodegenerative disorders.

Published: 8/21/2025
Inventor(s):
Kurt Brunden, Carlo Ballatore, Amos Smith, Virginia Lee, John Trojanowski
Keywords(s):
Aging, Neurodegenerative Diseases, Neurology, Small Molecule
Category(s):
Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics