Search Results - covid-19

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Intranasal Dantrolene Nanoparticle Use For Treatment Of Alzheimer's Disease

Intranasal delivering of dantrolene nanoparticles could potentially be used to inhibit memory loss and reduce amyloid plaques in patients with Alzheimer's disease.

Published: 3/12/2025
Inventor(s):
Huafeng Wei, Qing Cheng Meng, Ge Liang, Maryellen Eckenhoff
Keywords(s):
Aging, COVID-19, Nanotechnology, Neurodegenerative Diseases
Category(s):
Technology Classifications > Animal Health, Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Food Science and Nutrition, Technology Classifications > Research Tools & Reagents, Technology Classifications > Therapeutics

High-Throughput Approach to Identify New Lipid Nanoparticle Formulations for Vaccine and Drug Delivery

High-throughput in vivo screening method to identify lipid nanoparticle (LNP) formulations for local and systemic delivery for mRNA vaccines and cancer immunotherapies.

Published: 1/7/2025
Inventor(s):
Michael Mitchell, Alex Hamilton
Keywords(s):
Bioengineering, COVID-19, Drug Delivery, Gene Therapy, Immunology, Immunoncology, Immunotherapy, Infectious Disease, Nanotechnology
Category(s):
Technology Classifications > Testing & Measurement, Technology Classifications > Vaccines, Technology Classifications > Therapeutics

Lipid Nanoparticles That Specifically Target The Lungs

Lung-targeting lipid nanoparticles allowing organ specific mRNA delivery for gene therapy applications.

Published: 10/17/2024
Inventor(s):
Michael Mitchell, Lulu Xue
Keywords(s):
Bioengineering, COVID-19, Gene Therapy, Infectious Disease, Pulmonary
Category(s):
Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics, Technology Classifications > Vaccines

Adjuvanted Lipid Nanoparticles (LNPs) Enhance Protective Immunity Imparted by SARS-CoV-2 mRNA Vaccine

A lipid nanoparticle formulation that elicits a strong innate immune response for improved vaccine protection

Published: 10/1/2024
Inventor(s):
Michael Mitchell, Xuexiang Han, Drew Weissman, Mohamad Alameh
Keywords(s):
Bioengineering, COVID-19, Drug Delivery, Immunology, Infectious Disease, Nanotechnology
Category(s):
Technology Classifications > Materials, Technology Classifications > Vaccines

Low-Cost, Point-of-Care Test for Rapid Visual Diagnosis of COVID-19

A rapid, low-cost, portable swab-based SARS-CoV-2 biosensor whose test result can be detected with naked eye

Published: 6/26/2024
Inventor(s):
Cesar de la Fuente-Nunez, Marcelo Der Torossian Torres, Lucas Felipe de Lima, Andre Lopes Ferreira
Keywords(s):
Bioengineering, COVID-19, Infectious Disease
Category(s):
Technology Classifications > Diagnostics, Technology Classifications > Medical Devices

Novel Nanoparticle Composition Targeting Marginated Leukocytes

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Published: 1/12/2024
Inventor(s):
Jacob Myerson, Jacob Brenner, Vladimir Muzykantov, Landis Walsh, Priyal Patel
Keywords(s):
COVID-19, Drug Delivery, Infectious Disease, Inflammation, Nanotechnology, Pulmonary
Category(s):
Technology Classifications > Therapeutics

Repurposing of FDA-approved HER-inhibiting therapies for acute lung injury treatment

Mitigating ventilator-induced lung injury and acute respiratory distress syndrome through HER2/HER3 signaling pathway

Published: 1/5/2024
Inventor(s):
Susan Margulies
Keywords(s):
COVID-19
Category(s):
Technology Classifications > Therapeutics

Device for MRI Scanner Intra-Bore Disinfection

Magnetic field-safe device for rapid disinfection of MRI bore and other types of scanners (CT, PET, PET-MR, SPECT) that is effective against COVID19, MRSA and other pathogens.

Published: 1/10/2024
Inventor(s):
Norman Butler, James Pilla, Terence Gade, Gabor Mizsei
Keywords(s):
COVID-19, Infectious Disease, Radiology
Category(s):
Technology Classifications > Medical Devices, Technology Classifications > Imaging

Low-cost rapid diagnostic for COVID-19

A COVID-19 diagnostic approach, utilizing a SARS-CoV-2 binding biosensor, that allows for real-time virus detection, without the need for sample processing, ultimately leading to population-level surveillance, outbreak tracking, reduced healthcare costs, improved treatment outcomes, and saved lives.

Published: 1/5/2024
Inventor(s):
Cesar de la Fuente-Nunez, Marcelo Der Torossian Torres, William Reis de Araujo
Keywords(s):
Bioengineering, COVID-19, Infectious Disease
Category(s):
Technology Classifications > Diagnostics, Technology Classifications > Digital Health, Technology Classifications > Hardware & Components

Protein Drugs Encapsulated in Plant Cells as Low-Cost Prevention and Treatment of Lung Injury in COVID-19 Patients

Use of functional recombinant ACE2 and Angiotensin-(1-7) proteins to improve the clinical course of patients with symptomatic COVID-19 infection.

Published: 7/2/2024
Inventor(s):
Henry Daniell
Keywords(s):
COVID-19
Category(s):
Technology Classifications > Therapeutics
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