A CEST MRI method detects lactate in vivo by comparing lactate maps before and after administering a metabolic precursor contrast agent.
A CEST MRI method measures tumor glutaminase expression by comparing glutamate maps before and after glutamine or glutaminase blocker injection.
The technology measures multiple circulating biomarkers and applies machine learning to diagnose disease, classify stage, and assess therapy response.
The technology combines human ultrasound assessment with automatically extracted image features to classify malignancy risk and flag low-confidence cases for further evaluation.
The technology provides astatine-211 labeled sigma-2 ligand compounds and compositions for cancer treatment, radiotherapy administration, and chemosensitization.
Chimeric antigen receptor (CAR) T cell therapy targeting CA19-9, an antigen over-expressed in several cancers, including 80-90% of pancreatic cancers.
Molecular diagnostic using clamping fluorescent probes to amplify RNA detection signal of single-cell assay
A quick and inexpensive method to detect cancer early by exponentially amplifying rare and scarce cancer mutations.
A method to manipulate tumor-associated macrophages by targeting the mitochondrial electron transport chain, improving the efficacy of immune checkpoint blockade cancer therapies.
A flexible toolkit for human gene editing, activation, and repression that can be applied in orthogonally and in various disease models.