Molecular diagnostic using clamping fluorescent probes to amplify RNA detection signal of single-cell assay
A quick and inexpensive method to detect cancer early by exponentially amplifying rare and scarce cancer mutations.
A method to manipulate tumor-associated macrophages by targeting the mitochondrial electron transport chain, improving the efficacy of immune checkpoint blockade cancer therapies.
A flexible toolkit for human gene editing, activation, and repression that can be applied in orthogonally and in various disease models.
Benzofuranoindoline-containing fungal RiPP-derived compounds and analogs, plus pharmaceutical compositions, and administration methods for treating cancers, including leukemia.
A computational method for calculating the dose, Linear Energy Transfer and Relative Biological Effectiveness of proton treatment planning and optimization.
A method of proton beam therapy using a single energy proton beam delivered at multiple angles to the tumor.
A single-frame, multi-exposure time optical method enabling accurate extraction of absolute speckle decorrelation time and optimized for recovery of absolute deep-tissue blood flow.
A method to combine two or three monoclonal antibodies (mABs) into one treatment to successfully bind to multiple cancer cell surface epitopes and promote targeted degradation by phagocytosis.
Inhibitors and tools to block the local formation of steroid hormones in hormone-dependent malignancies of the prostate, breast and endometrium