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Photoactivated Selective Release (PHASR) of Droplets from Microwell Arrays

A photoresponsive polymer layer that can be integrated into microfluidic devices for selective release of unique droplets

Published: 8/2/2024
Inventor(s):
Daeyeon Lee, Junhyong Kim, Yongwon Choi, Syung-Hun Han
Keywords(s):
Artificial Intelligence (AI) & Machine Learning, Microfluidics, Nanotechnology
Category(s):
Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Research Tools & Reagents

Fluorescent Probes for the Selective Detection of Alzheimer's and Parkinson's Diseases

Bimane-based fluorescent probes with turn-on fluorescence in the presence of α-synuclein, a known hallmark of Altzeimer’s and Parkinson’s diseases.

Published: 6/27/2024
Inventor(s):
E. James Petersson, Venkatesh Yarra
Keywords(s):
 
Category(s):
Technology Classifications > Research Tools & Reagents

Low Cost, Mobile, Wearable EEG Device with High Quality Nanowire Sensors

Mobile, wearable, low cost electro-encephalogram (EEG) devices that offer research grade signals may provide a wealth of information regarding the brain states of individuals. This knowledge can be effectively utilized to develop personalized treatment protocols in medicine and individual customer–based advertisements for marketing.

 

The inventors aim to establish sensitive, objective biomarkers that can vastly improve the quality of life of patients and customer satisfaction in business. This breakthrough device is being developed and commercialized through a University of Pennsylvania start-up, Cogwear LLC.

Published: 6/26/2024
Inventor(s):
Michael Platt, Arjun Ramakrishnan, Naz Belkaya
Keywords(s):
 
Category(s):
Technology Classifications > Business Ideas, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Research Tools & Reagents, Technology Classifications > Hardware & Components

High-Throughput and Independent Temperature Regulation In Biological Samples

A device that provides independent thermal regulation for biological samples in a 96-well microwell plate.

Published: 6/6/2024
Inventor(s):
Lukasz Bugaj, Brian Chow, William Benman, Zikang (Dennis) Huang
Keywords(s):
Bioengineering, Platform Technology
Category(s):
Technology Classifications > Hardware & Components, Technology Classifications > Research Tools & Reagents, Technology Classifications > Testing & Measurement

Biodegradable Batteries Operational In The Air, Environment, And Soil

A method to fabricate batteries from biodegradable materials that can operate in the environment, such as on or under soil, and are scalable in size.

Published: 5/20/2024
Inventor(s):
Jingwen Zhang, Mark Allen
Keywords(s):
Electronic Materials, Hydrogels, Internet of Things, Nanotechnology, Soft Materials
Category(s):
Technology Classifications > Research Tools & Reagents, Technology Classifications > Agriculture & Environment, Technology Classifications > Energy, Technology Classifications > Materials

Ultrasensitive, High-Throughput, Single-Scale Detection of Extracellular Vesicles

An optofluidic platform to detect extracellular vesicles (EVs) at the single-particle level by parallelizing droplet generation and analysis of EVs.

Published: 2/26/2024
Inventor(s):
David Issadore, Zijian Yang
Keywords(s):
Bioengineering, Microfluidics, Optics & Photonics , Platform Technology
Category(s):
Technology Classifications > Diagnostics, Technology Classifications > Research Tools & Reagents, Technology Classifications > Testing & Measurement

Base Metal Catalysts For Cyclic Conjugated Polymer Formation

A class of base metal catalysts (as opposed to expensive platinum and heavier group metals) with facile preparation methods for cyclic conjugated polymer synthesis.

Published: 1/29/2024
Inventor(s):
Daniel Mindiola, John Russell
Keywords(s):
Soft Materials
Category(s):
Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials, Technology Classifications > Research Tools & Reagents

PET Radiotracers for Diagnosis and Patient Stratification of Neurodegenerative Disorders

Small molecules that bind to alpha-synuclein deposition and can be used for PET imagining in patients with synucleinopathies

Published: 6/6/2024
Inventor(s):
Robert Mach, E. James Petersson
Keywords(s):
Imaging Agents, Neurodegenerative Diseases, Radiology, Small Molecule
Category(s):
Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Diagnostics, Technology Classifications > Imaging, Technology Classifications > Research Tools & Reagents

Revolutionizing CT Imaging: Gold Nanoparticles with Biodegradable Polymer Encapsulation

Innovative CT contrast agent using biodegradable polymer-encapsulated gold nanoparticles for enhanced imaging and safe excretion.

Published: 2/12/2024
Inventor(s):
David Cormode
Keywords(s):
 
Category(s):
Technology Classifications > Diagnostics, Technology Classifications > Imaging, Technology Classifications > Research Tools & Reagents

Stable Biological Membrane Mimetic For Enhanced Protein Recruitment

Synthetic biological alternative to natural lipids for conjugation with nitrilotriacetic acid (NTA) for enhanced His-tagged protein interaction and long-term stability.

Published: 10/16/2023
Inventor(s):
Virgil Percec, Qi Xiao, Matthew Good
Keywords(s):
Bioengineering, Platform Technology
Category(s):
Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Research Tools & Reagents
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