Search Results - gene+editing

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Human Artificial Chromosome Generation Technology

Technology allowing efficient formation, delivery, isolation, and enrichment of single-copy Human Artificial Chromosome (HAC) for use in research, plant production, gene and cell therapy and more.

Published: 9/19/2025

LNP + Squeeze: Enhancing Chimeric Antigen Receptor T-Cell Generation via Mechanoporation and Lipid Nanoparticles

Synergistic combination of mechanoporation and lipid nanoparticle (LNP) based transfection for an efficient, non-viral method of gene transfer to generate CAR-T cell therapies.

Published: 8/28/2025

The First Curative Treatment of Phenylketonuria Using Genetic Engineering Approaches

The base editing of phenylalanine hydroxylase enzyme in the liver to restore phenylalanine metabolism and prevent neurotoxic effects.

Published: 8/21/2025

Ligand-Tethered Lipid Nanoparticles for Targeted RNA Delivery to Treat Liver Fibrosis

A new class of anisimide-functionalized lipids that enables targeted delivery of lipid nanoparticles (LNPs) to activated fibroblasts in the liver.

Published: 10/10/2025