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Passive multidirectional illumination in light-sheet flourecense microscopy

Problem: Light-sheet fluorescence microscopy enables rapid scanning of biological samples to reconstruct a 3-dimensional image of the sample. However, images generally contain artifacts (shadows, stripes, etc.) that are caused by illumination inhomogeneity due to absorption or scattering within the sample. These artifacts can occlude observation of...

Published: 3/1/2019

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