Search Results - neurodegenerative+diseases

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Novel Compounds for Treatment for Friedreich Ataxia

New compounds identified through high throughput screening which improve mitochondrial function of Friedreich ataxia cells.

Published: 8/6/2026
Inventor(s):
Robert Wilson
Keywords(s):
Neurodegenerative Diseases, Orphan Disease
Category(s):
Technology Classifications > Therapeutics

Intranasally-Delivered Therapy for Treatment of Amyotrophic Lateral Sclerosis

Intranasal delivery of dantrolene nanoparticles can improve motor neuron function, muscle strength, and movement coordination and can offer therapeutic benefits for treatment of Amyotrophic Lateral Sclerosis (ASL).

Published: 8/6/2026
Inventor(s):
Huafeng Wei
Keywords(s):
Genetic Disorders, Inflammation, Neurodegenerative Diseases, Neurology, Pulmonary, Small Molecule
Category(s):
Technology Classifications > Therapeutics

An Implantable Device for Restoring Muscle Function in Nerve or Muscle Impairment

A neuroprosthetic implant that uses existing nerve or muscle signals to replace damaged muscle and restores movement

Published: 8/6/2026
Inventor(s):
Niv Milbar, Cynthia Sung, Flavia Vitale, Gabriel Unger, Raghav Garg
Keywords(s):
Bioengineering, Neurodegenerative Diseases, Neurology, Surgery
Category(s):
Technology Classifications > Medical Devices, Technology Classifications > Robotics

Ultrafast, Sensitive, And Long-Lasting Bioelectrochemical Transistors

Supramolecular crown ethers and fluorinated polymers enable the formation of high ionic conductivity, water-impermeable artificial ion channels for bioelectronic transistor applications.

Published: 8/6/2026
Inventor(s):
Yuanwen Jiang, Yuhui Wang
Keywords(s):
Bioengineering, Electronic Materials, Nanotechnology, Neurodegenerative Diseases, Neurology, Platform Technology
Category(s):
Technology Classifications > Diagnostics, Technology Classifications > Hardware & Components, Technology Classifications > Materials, Technology Classifications > Medical Devices

An All-In-One “Swiss Army Knife” Tool To Edit Genes And Regulate Their Expression Without Off-Target Effects And Toxicity

A flexible toolkit for human gene editing, activation, and repression that can be applied in orthogonally and in various disease models.

Published: 8/6/2026
Inventor(s):
Xue Sherry Gao, Tyler Daniel, Hongzhi Zeng, Qichen Yuan
Keywords(s):
Bioengineering, Cell Therapy, Gene Editing, Genetic Disorders, Neurodegenerative Diseases, Obesity Metabolic Disease and Diabetes, Oncology, Orphan Disease, Pulmonary
Category(s):
Technology Classifications > Research Tools & Reagents, Technology Classifications > Therapeutics

Pharmacological Treatment for Sleep Disorders Improving Sleep Quality & Architecture

Targeting Heat Shock Factor 1 (HSF1) via gene therapy or using pharmacological compounds targeting HSF1 (e.g. geranylgeranylacetone or macrocyclic peptides) can increase sleep stability, promote deeper sleep, reduce sleep fragmentation, and improve recovery from sleep loss.

Published: 8/6/2026
Inventor(s):
Akhilesh Basi Reddy, Shintaro Yamazaki
Keywords(s):
Aging, Drug Target, Gene Therapy, Neurodegenerative Diseases, Protein/Peptide (Non-Antibody), Small Molecule, Women's Health
Category(s):
Technology Classifications > Therapeutics

An Accessible and Automated Device to Diagnose Nerve and Muscle Disorders

A device consisting of electrode patches, a control box, and software for automated nerve conduction studies.

Published: 8/6/2026
Inventor(s):
Josh Baxter, Flavia Vitale, Margaret (Maggie) Wagner, Quinn Tate
Keywords(s):
Artificial Intelligence (AI) & Machine Learning, Bioengineering, Neurodegenerative Diseases, Neurology, Orthopedics, Software
Category(s):
Technology Classifications > Hardware & Components, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Testing & Measurement

T Cells Targeting Misformed Proteins to Treat Neurodegenerative and Muscular Diseases

Antigen-specific immunotherapy with engineered cytotoxic T cells targeting misformed proteins to treat neurodegenerative and muscular diseases.

Published: 8/6/2026
Inventor(s):
Ning (Jenny) Jiang, Shahab (Shawn) Chizari
Keywords(s):
Bioengineering, Cell Therapy, Immunology, Immunotherapy, Inflammation, Neurodegenerative Diseases
Category(s):
Technology Classifications > Diagnostics, Technology Classifications > Research Tools & Reagents, Technology Classifications > Therapeutics

Intranasally-Delivered Therapy For The Treatment Of Depression And Dementia

Intranasal nasal dantrolene nanoparticles alone, or in combination with lithium, can provide protection against depression and dementia with minimal or no side effects.

Published: 8/6/2026
Inventor(s):
Huafeng Wei
Keywords(s):
Aging, Immunology, Immunoncology, Infectious Disease, Inflammation, Neurodegenerative Diseases
Category(s):
Technology Classifications > Therapeutics

Intranasal Dantrolene Nanoparticle Use For Treatment Of Alzheimer's Disease

Intranasal delivering of dantrolene nanoparticles could potentially be used to inhibit memory loss and reduce amyloid plaques in patients with Alzheimer's disease.

Published: 8/6/2026
Inventor(s):
Huafeng Wei, Qing Cheng Meng, Ge Liang, Maryellen Eckenhoff
Keywords(s):
Aging, COVID-19, Nanotechnology, Neurodegenerative Diseases
Category(s):
Technology Classifications > Animal Health, Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Food Science and Nutrition, Technology Classifications > Research Tools & Reagents, Technology Classifications > Therapeutics
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