Lung-targeting lipid nanoparticles allowing organ specific mRNA delivery for gene therapy applications.
Lipid nanoparticles (LNPs) with reversibly attached branched lipid tails for the delivery of mRNA for gene therapy.
A combinatory formulation for oral care products that enhances antimicrobial specificity, anti-plaque potency and prevents tooth decay.
Diverse difluoromethylene scaffolds via novel, organodifluorine synthons.
Using mRNA-LNPs to deliver forkhead box protein 3 (Foxp3) to CD4+ T cells to engineer Foxp3-positive T (FP3T) cells with immunosuppressive properties.
A photoresponsive polymer layer that can be integrated into microfluidic devices for selective release of unique droplets
A hydrogel-based adhesive with a hydrophobic backing layer protects it from exposure to water and offers painless removal and easy repositioning.
A library of easily synthesized ionizable amphiphilic Janus dendrimer (IAJD) compounds that deliver mRNA either to targeted organs or multiple organs, depending on the IAJD design.
Method to transfer wettability properties of a mold to microfluidic devices, defining hydrophobic/hydrophilic regions through variable perfluoropolyether concentration.
A scalable heterogeneous nanoparticle film with controllable manufacturing methods with tunable properties that could be useful for a variety of applications.