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Search Results - michael mauk

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A method for highly selective nucleic acid enrichment for sensitive detection of mutations in cancer and genectic conditions.
Brief Description: This technology increases the fraction of clinically relevant, rare mutant alleles (DNA and/or RNA) to enable high sensitivity detection with common downstream methods such as capped (XNA or PNA) PCR, ddPCR, and sequencing. Motivation:Liquid biopsy is a simple, minimally invasive, rapidly developing diagnostic method to analyz...
Published: 6/24/2019   |   Inventor(s): Jinzhao Song, Haim Bau, Michael Mauk, Jorrit Hegge, John van der Oost
Keywords(s):  
Category(s): Diagnostics, Hardware, Circuits, & Sensors, Medical Devices, Research Tools & Reagents, Veterinary & Animal Health
High efficiency, superhydrophobic clamshell plasma separator for point-of-care diagnostics
Membrane-based, sedimentation-assisted plasma separator InventorHaim H. Bau, Professor of Mechanical Engineering and Applied MechanicsChangchun Liu, Assistant Research ProfessorMichael Mauk, Visiting Assistant Clinical ProfessorProblemHigh sensitivity, point-of-care clinical tests, such as HIV viral load, require large volumes of plasma extracted f...
Published: 1/31/2018   |   Inventor(s): Haim Bau, Changchun Liu, Michael Mauk
Keywords(s): Engineering
Category(s): Diagnostics, Medical Devices
A portable, real-time enzymatic amplification reactor with dry storage of reagents
Brief Description: Point-of-care diagnostic system for nucleic acid-based analysis -----------------------------------------------------------------------------------------------------------------------------------------Technology: The Bau lab has developed a pre-loaded analysis module with reagents stored within a barrier material capab...
Published: 2/8/2017   |   Inventor(s): Haim Bau, Michael Mauk
Keywords(s):  
Category(s): Diagnostics, Medical Devices
Nuclemeter: a yardstick for quantifying nucleic acids undergoing enzymatic amplification
Point-of-care, reaction-diffusion column-based, non-instrumented device for real-time visual measurement of viral load in resource-limited settings, in the clinic, and at homeInventorHaim H. Bau, Professor of Mechanical Engineering and Applied MechanicsChangchun Liu, Research Assistant Professor, Mechanical Engineering and Applied MechanicsMichael ...
Published: 1/20/2016   |   Inventor(s): Haim Bau, Changchun Liu, Michael Mauk
Keywords(s): Engineering, Nanotechnology
Category(s): Diagnostics, Research Tools & Reagents
Rapid plasma separator for point-of-care diagnostics and viral load detection that does not require electrical power
Membrane-based, sedimentation-assisted plasma separator from whole blood for clinical testsInventorHaim H. Bau, Professor of Mechanical Engineering and Applied MechanicsChangchun Liu, Assistant Research ProfessorMichael Mauk, Visiting Assistant Clinical ProfessorProblemHigh sensitivity, point-of-care clinical tests, such as HIV load, require large ...
Published: 12/8/2015   |   Inventor(s): Haim Bau, Changchun Liu, Michael Mauk
Keywords(s): Amino Acid, Engineering
Category(s): Diagnostics, Medical Devices