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Single viral vector for expression of both CAR/TCR and immune modulators for cancer immunotherapy

A single lentiviral vector system as an expression platform for constitutive immune receptor expression and inducible antigen-dependent immunomodulatory molecule expression in primary immune cells for enhanced immunotherapy efficacy

Published: 11/11/2024
Inventor(s):
Daniel Powell, Anze Smole, Avery Posey
Keywords(s):
CAR T-cell Enhancing Technology
Category(s):
Technology Classifications > Research Tools & Reagents, Technology Classifications > Therapeutics