Using mRNA-LNPs to deliver forkhead box protein 3 (Foxp3) to CD4+ T cells to engineer Foxp3-positive T (FP3T) cells with immunosuppressive properties.
Targeting retinoic acid (RA) synthesizing enzymes or RA receptors with small molecules boosts the immune system towards a tumor rejection response
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A method that maintains the viability and function of NK cells following cryopreservation, enabling the production, storage, and transportation of therapeutic doses of NK cells to treatment centers.
Hydroxycholesterols are used to formulate lipid nanoparticles (LNPs) for enhanced mRNA delivery into T cells.
A dietary supplement that protects brain cells from the effects of TBI and concussion
A platform technology utilizing synthetic organelles to modulate cell cycle, cell behavior, and stemness/differentiation status which could be used for cell engineering, cell therapy etc.
Nanoparticles for potent encapsulation and delivery of therapeutic molecules for prenatal fetal therapy in the amniotic sac
Ten candidate serum and synovial protein levels provide early indication of joint impairment in lysosomal storage disorders.
The deep learning algorithm retrospectively improves the resolution of routine medical images (e.g., CT, MRI, etc.) without the need for increased radiation or scan time.