Search Results - eric+witze

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Pyrazole Derivatives for the Treatment of Lung Cancer Tumors

A class of pyrazole derivatives that inhibit palmitoyl-transferases, resulting in increasing cancer cell responsiveness to epidermal growth factor receptor inhibitor and KRas mutant lung cancer growth inhibition as a single agent.

Published: 5/31/2024

Novel Compounds for Sensitization of Cancer Cells to EGFR Inhibitors

Method allowing to increase sensitivity and/or overcome resistance to EGFR inhibitors in cancer cells through inhibition of palmitoyltransferase DHHC20. 

Published: 1/10/2024
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