Search Results - eric+witze

2 Results
Sort By:

Pyrazole Derivatives for the Treatment of Lung Cancer Tumors

A class of pyrazole derivatives that inhibit palmitoyl-transferases, resulting in increasing cancer cell responsiveness to epidermal growth factor receptor inhibitor and KRas mutant lung cancer growth inhibition as a single agent.

Published: 2/9/2024
Inventor(s):
George Burslem, Eric Witze
Keywords(s):
Oncology, Small Molecule
Category(s):
Technology Classifications > Therapeutics

Novel Compounds for Sensitization of Cancer Cells to EGFR Inhibitors

Method allowing to increase sensitivity and/or overcome resistance to EGFR inhibitors in cancer cells through inhibition of palmitoyltransferase DHHC20. 

Published: 1/10/2024
Inventor(s):
Eric Witze
Keywords(s):
Oncology
Category(s):
Technology Classifications > Therapeutics