Innovation at Penn
Browse Penn-owned technologies available for licensing.
Search Results - jay+dorsey
Rapid and ultrasensitive profiling of EGFRvIII mutations in cancer and normal tissue
A method to rapidly detect the presence of EGFRvIII mutations in cancers and normal tissue using digital PCR. Problem: Glioblastoma multiforme (GBM) is a devastating brain cancer with poor prognosis. EGFRvIII is a mutation in the Extracellular Growth Factor Receptor that frequently occurs in GBM tumors. Targeting EGFRvIII mutations is an emerging...
Chemical Processes and Synthesis
Research Tools & Reagents
X-ray irradiation-activated hydrogel for effective on-demand treatment of glioblastoma and other tumors
Primary tumor reoccurrence often occurs following surgical resection in glioblastoma multiforme patients. Current hydrogel approaches deliver therapeutics using light or pH, but these approaches are limited by the tumor microenvironment. Researchers have developed an injectable hydrogel with unique materials that can be activated by X-ray irradiation...
Therapeutics & Vaccines
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