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Search Results - susan margulies

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Novel therapeutic use of protein kinase RNA-like endoplasmic reticulum kinase (PERK) inhibitor for acute lung injury treatment
Mitigating lung injury and lung inflammation through PERK pathway inhibition Problem: Acute lung injury, induced by long-term treatment with a mechanical ventilator, and acute respiratory distress syndrome (ARDS) affects 190,000 patients per year in the United States, with associated mortality of 35-40%. The highest numbers of deaths are in patients...
Published: 2/5/2020   |   Inventor(s): Susan Margulies
Keywords(s):  
Category(s): Therapeutics & Vaccines
Repurposing of FDA-approved HER-inhibiting therapies for acute lung injury treatment
Mitigating ventilator-induced lung injury and acute respiratory distress syndrome through HER2/HER3 signaling pathway Problem: Acute lung injury, such as that induced by long-term treatment with a mechanical ventilator, and acute respiratory distress syndrome (ARDS) affects 190,000 patients per year in the United States, with associated mortality...
Published: 1/31/2020   |   Inventor(s): Susan Margulies
Keywords(s): COVID-19
Category(s): Therapeutics & Vaccines